血清降钙素原对经皮肾镜碎石术后尿脓毒血症的早期诊断价值

发布时间：2018-03-28 15:14

本文选题：尿脓毒血症　切入点：降钙素原　出处：《山东医药》2016年04期

【摘要】：目的探讨血清降钙素原(PCT)对经皮肾镜碎石术后尿脓毒血症的早期诊断价值。方法回顾性分析185例因上尿路结石并泌尿道感染行经皮肾镜碎石术患者临床资料。其中术后并发尿脓毒血症(观察组)94例,术后未并发尿脓毒血症(对照组)91例。检测两组术前及术后24 h血清PCT、CRP和WBC计数。受试工作特征曲线(ROC)评价血清PCT对经皮肾镜碎石术后尿脓毒血症的早期诊断价值。结果两组术前血清PCT、WBC计数比较P均0.05,CRP比较P0.05;与术前比较,观察组术后24 h血清PCT水平升高(P0.05),CRP、WBC计数差异无统计学意义(P均0.05)。血清PCT诊断经皮肾镜碎石术后尿脓毒血症的ROC曲线下面积为0.872(95%CI:0.632~0.975);血清PCT诊断尿脓毒血症的敏感度为90.24%,特异度为82.57%,阳性预测值为81.35%,阴性预测值为88.37%。结论血清PCT可作为早期诊断经皮肾镜碎石术后尿脓毒血症的可靠预测指标。
[Abstract]:Objective to investigate the value of serum procalcitonin (PCT) in the early diagnosis of urinary sepsis after percutaneous nephrolithotripsy. Methods the clinical data of 185 patients with upper urinary calculi and urinary tract infection underwent percutaneous nephrolithotripsy were retrospectively analyzed. There were 94 cases of urinary sepsis in the observation group. There were 91 cases of urinary sepsis after operation (control group, 91 cases). Before and 24 hours after operation, the levels of serum PCT CRP and WBC were measured in both groups. The value of serum PCT in the early diagnosis of urinary sepsis after percutaneous nephrolithotripsy was evaluated. Results the WBC count of serum PCT in both groups was higher than that before operation (P < 0.05) and CRP was higher than that before operation (P < 0.05), and compared with that before operation (P < 0.05). There was no significant difference in serum PCT count between two groups 24 hours after operation. The area under ROC curve of serum PCT for diagnosis of urinary sepsis after percutaneous nephrolithotripsy was 0.87295 CI: 0.632and the sensitivity of serum PCT in the diagnosis of urinary sepsis was as follows: the sensitivity of serum PCT in the diagnosis of urinal sepsis was 0.87 2%, 0.62% and 0.975% respectively, and the sensitivity of serum PCT in the diagnosis of urinary sepsis was higher than that in control group (P < 0.05). 90.24, the specificity was 82.57, the positive predictive value was 81.35, the negative predictive value was 88.37. Conclusion Serum PCT can be used as a reliable predictor for early diagnosis of urinary sepsis after percutaneous nephrolithotripsy.
【作者单位】：泸州医学院附属医院;
【基金】：四川省科学技术厅基金项目(14JC0801) 泸州市科研基金项目(2013LZLY-J26)
【分类号】：R699

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