七叶皂苷钠联合迈之灵对阴囊术后肿胀的疗效观察

发布时间：2018-04-11 10:25

本文选题：迈之灵 + 注射用七叶皂苷钠　；参考：《青海大学》2014年硕士论文

【摘要】：目的：研究七叶皂苷钠及其联合迈之灵治疗阴囊术后肿胀的临床效果，从而为阴囊术后肿胀患者康复提供更好的治疗。方法：附睾炎术后患者共132例，根据从术后第一天开始用药不同随机进行分组：治疗组：单用七叶皂苷钠组(A1:32例),单用迈之灵组(A2:35例),七叶皂苷钠联合迈之灵治疗组(A3:45例)，，其他处理与对照组相同；对照组：不用上述药物只行常规对症治疗组（B:20例）。每组病例术后均采用卧床休息、阴囊术后常规护理等对症治疗。观察分析应用七叶皂苷钠及其联合迈之灵在治疗组中的愈合情况，分别观察分析治疗组与对照组术后阴囊肿胀程度及恢复时间、切口愈合时间的差异性，并观察治疗组中在术后药物常见不良反应的差异性。对数据资料行统计学分析，统计方法：运用SPSS17.0统计软件行数据资料分析。结果：附睾炎术后患者中治疗组（A1、A2、A3）较对照组(B)在术后阴囊肿胀程度及恢复时间（48h、96h、7d时均有统计学意义，P0.05）、切口愈合时间（P0.05）有明显优势；单用七叶皂苷钠组(A1)和单用迈之灵组(A2)在术后阴囊肿胀程度及恢复时间（48h、96h、7d时比较均无统计学意义，P0.05）、切口愈合时间（P0.05）无明显差异，单用七叶皂苷钠组(A1)较单用迈之灵组(A2)术后药物常见不良反应多见（P0.05）；七叶皂苷钠联合迈之灵片治疗组（A3）在术后阴囊肿胀程度及恢复时间（48h、96h、7d时比较均有统计学意义，P 0.05)、切口愈合时间（P0.05）明显优于单用七叶皂苷钠组(A1)及单用迈之灵组(A2)，七叶皂苷钠联合迈之灵片治疗组（A3）较单用七叶皂苷钠组(A1)在术后药物常见不良反应少见（P0.05），但较单用迈之灵组(A2)术后常见药物不良反应多见（P0.05）；说明七叶皂苷钠联合迈之灵治疗阴囊术后肿胀更有效。结论：1、七叶皂苷钠、迈之灵均是对抗渗出、消肿胀极为有效的药物,对阴囊术后肿胀效果明显；2、二者联合用药更有效，患者术后切口愈合时间缩短，可短期内出院，并减少医生工作量。
[Abstract]:Aim: to study the clinical effect of sodium aescinate and its combination with mazilin in the treatment of postoperative scrotal swelling, and to provide better treatment for the patients with scrotum postoperative swelling.Methods: 132 patients with epididymitis were treated after operation.According to the first day after operation, the patients were randomly divided into two groups: the treatment group: A1: 32 cases were treated with sodium aescinate alone, the group A 2: 35 cases were treated with Maxiling alone, and 45 cases were treated with sodium aescinate combined with maisuling. The other treatments were the same as those in the control group.Control group: 20 cases were treated with routine treatment group without the above drugs.Patients in each group were treated with bed rest and routine nursing after scrotum operation.To observe and analyze the healing condition of the treatment group with sodium aescinate and its combination with Maxiline, and observe the difference of the degree of scrotum swelling, recovery time and wound healing time after operation between the treatment group and the control group.The differences of common adverse drug reactions in the treatment group were observed.Statistical analysis of data data, statistical methods: the use of SPSS17.0 statistical software data analysis.Results: compared with the control group, there were significant differences in the degree of scrotal swelling and recovery time between the treatment group and the control group (P 0.05) and the wound healing time (P 0.05).Sodium aescinate alone was more common adverse drug reaction (P 0.05) than that of Maxiling group (P < 0.05), and the degree of scrotum swelling and recovery time of scrotum was significantly higher in the group treated with sodium aescinate combined with mazhiling tablet than that in group A _ 2. There was significant difference in the degree of scrotum swelling and recovery time at the end of 96h and 7d after operation.The common adverse drug reactions (P0.05) were more commonly seen in the group A _ 2 than those in the group A _ 2 alone, indicating that sodium aescinate combined with maziling was more effective in the treatment of postoperative swellings in scrotum.Conclusion 1%, sodium aescinate and maisuling are effective drugs for anti-exudation and anti-swelling. The combined use of the two drugs is more effective, and the wound healing time is shortened, and the patients can be discharged from hospital in a short time.And reduce the workload of doctors.
【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R699.8

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