良性前列腺增生患者术后再发前列腺癌的临床特点

发布时间：2018-04-16 00:08

  本文选题：前列腺癌 + 良性前列腺增生　； 参考：《中国老年学杂志》2017年02期

【摘要】：目的探讨良性前列腺增生症(BPH)患者术后再发前列腺癌的临床特点。方法分析24例BPH术后再发前列腺癌患者资料,根据主诉分为肉眼血尿组和排尿困难组,又根据BPH手术方式分为前列腺开放手术组与经尿道前列腺电切术(TURP)术组,观察两组间发病年龄、与BPH手术间隔时间、前列腺体积、血前列腺特异性抗原(PSA)水平及Gleason评分的差别,分析低分化腺癌、Ⅳ期和硬结发生率。结果前列腺开放手术与TURP术后两组发病年龄、术后间隔时间、前列腺体积、血PSA、临床分期(F=0.727,P=0.403)无显著性差异。血尿组与排尿困难两组发病年龄、术后间隔时间、血PSA、Gleason评分、低分化腺癌发病率无显著性差异,血尿组前列腺体积较排尿困难组大(F=5.923,P=0.024)。血尿组硬结发生率明显高于排尿困难组(P0.05),临床分期晚于排尿困难组(P0.05)。结论 BPH手术治疗(包括TURP)后再发的前列腺癌其临床表现和治疗原则基本同原发性前列腺癌。手术仅切除增生腺体,存留压迫、萎缩变形之外周带可能是术后前列腺癌再发的主要起源,再发癌可能与前列腺干细胞增殖、演变有关。BPH术后定期随访观察非常重要,可尽早发现癌变,做到早诊断早治疗。
[Abstract]:Objective to investigate the clinical features of recurrent prostate cancer in patients with benign prostatic hyperplasia (BPH).Methods Twenty-four patients with recurrent prostate cancer after BPH were divided into naked hematuria group and dysuria group according to the main complaint. The patients were divided into open prostate operation group and transurethral resection of prostate group according to BPH operation.The age of onset, the interval between operation and BPH, the volume of prostate, the level of serum prostate specific antigen (PSA) and the Gleason score were observed, and the incidence of poorly differentiated adenocarcinoma, stage 鈪，

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