腹膜透析与血液透析对尿毒症患者贫血的影响

发布时间：2018-04-16 03:02

本文选题：尿毒症 + 贫血　；参考：《山东医药》2017年45期

【摘要】：目的探讨腹膜透析(PD)与血液透析(HD)对尿毒症患者贫血的影响。方法 115例尿毒症患者按照透析方式不同分为PD组55例、HD组60例,PD组执行持续非卧床PD方案,采用葡萄糖浓度为1.5%和2.5%的PD液,二者比例为3∶1,每日换液8 000 m L,每周透析7 d。HD组采用HD,每周3次,每次4 h。以实验开始为起点,两组均持续透析8周,测定两组透析前后血清红细胞计数(RBC)、血红蛋白(Hb)、ALB(ALB)、C反应蛋白(CRP)、甲状旁腺激素(PTH),以及铁代谢指标,如血清铁(SI)、铁蛋白(SF)、转铁蛋白(TF)、转铁蛋白饱和度(TSAT%),并进行比较。结果透析前两组血清RBC、HB、ALB、PTH、CRP及铁代谢指标比较,P均0.05;同组内透析前后各指标比较,P0.05;透析后与HD组比较,PD组血清RBC、Hb升高,ALB、PTH、CRP、SF水平低(P均0.05)。结论 PD对尿毒症患者贫血状态的改善优于HD。
[Abstract]:Objective to investigate the effects of peritoneal dialysis (PD) and hemodialysis (HD) on anemia in uremic patients.Methods 115 patients with uremia were divided into PD group (55 cases), HD group (60 cases) and PD group (60 cases).The ratio of the two was 3: 1, 8 000 mL per day, and HD was given 3 times a week for 4 hours in 7 d.HD dialysis group.Starting from the beginning of the experiment, the two groups were continuously dialyzed for 8 weeks. Before and after hemodialysis, serum red blood cell count (RBC), hemoglobin (HB), ALB (ALBN) C-reactive protein (CRPN), parathyroid hormone (PTH), and iron metabolism were measured.For example, serum ferritin, ferritin, ferritin, transferrin, transferrin saturation and TSATT were compared.Results before dialysis, the levels of CRP and iron metabolism in the two groups were both 0.05, P 0.05, P 0.05, respectively, and the levels of serum RBCnHb in PD group were higher than those in HD group (P < 0.05), and the levels of serum RBCU HB in PD group were higher than those in HD group (P < 0.05).Conclusion PD is superior to HD in improving anemia in uremic patients.
【作者单位】：安徽医科大学第一附属医院;铜陵市立医院;
【基金】：安徽省自然科学基金(1308085MH155)
【分类号】：R692.5

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