不同手术方案治疗老年T2期肾细胞癌的疗效及安全性比较

发布时间：2018-04-18 10:25

本文选题：肾细胞癌 + 肾癌根治术　；参考：《中国老年学杂志》2017年05期

【摘要】：目的对比分析传统开放性肾癌根治术和后腹腔镜肾癌根治术治疗老年T2期肾细胞癌(RCC)的安全性和疗效。方法接受治疗的68例老年T2期RCC患者的临床资料根据手术方式的不同分成观察组32例,采用后腹腔镜手术和对照组36例,采用传统开放术。比较两组基本资料、术后炎性指标水平及住院时间、费用、治疗有效率等指标。结果两组基本资料无统计学意义(P0.05)。观察组术中出血量、住院时间均明显低于对照组(P0.05);两组住院费用、治疗有效率及并发症发生率均无统计学意义(P0.05)。两组术后第1天的各炎症指标水平差异无统计学意义(P0.05);而观察组术后第7天的C反应蛋白(CRP)(t=2.505,P=0.015)与白细胞介素(IL)-6(t=2.537,P=0.014)水平均明显低于对照组。结论后腹腔镜肾癌根治术在老年T2期RCC患者中安全性及疗效均良好。
[Abstract]:Objective to compare the safety and efficacy of traditional open renal cell carcinoma radical resection and retroperitoneal laparoscopic radical nephrectomy in the treatment of aged patients with stage T2 renal cell carcinoma (RCCs).Methods 68 elderly patients with stage T2 RCC were divided into observation group (n = 32), retroperitoneal laparoscopic operation (n = 36) and control group (n = 36).The basic data, postoperative inflammatory index level, hospitalization time, cost and effective rate of treatment were compared between the two groups.Results there was no significant difference in basic data between the two groups (P 0.05).The amount of intraoperative bleeding and the length of hospitalization in the observation group were significantly lower than those in the control group (P 0.05), but there was no significant difference between the two groups in the cost of hospitalization, the effective rate of treatment and the incidence of complications.There was no significant difference between the two groups on the first day after operation (P 0.05), but the levels of C-reactive protein (CRP) and interleukin (IL) -6 tir 2.537U P0. 014) in the observation group were significantly lower than those in the control group on the 7th day after operation.Conclusion Laparoscopic radical resection of renal cell carcinoma is safe and effective in elderly patients with stage T 2 RCC.
【作者单位】：南充市中心医院泌尿外科;
【分类号】：R737.11

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