肾盂及输尿管取石术患者术后切口感染病原菌分布与耐药性及预后分析

发布时间：2018-04-24 19:38

本文选题：肾盂及输尿管取石术 + 切口感染　；参考：《中华医院感染学杂志》2017年23期

【摘要】：目的调查分析121例肾盂及输尿管取石术患者术后切口感染的病原菌分布及多种耐药菌耐药性情况,以期为预防感染的发生及感染的后期治疗提供帮助。方法回顾性分析2013年7月-2015年7月医院收治的肾盂及输尿管取石术患者489例,对其中121例术后切口感染患者进行调查分析,取其标本做细菌培养和药敏试验,分析术后感染多种耐药菌分布及其耐药性情况。结果 489例肾盂及输尿管取石术患者中121例发生术后切口感染,感染率为24.74%;传统开放性切开术后切口感染率最高,感染率为40.32%;121例送检标本分离出病原菌128株,以革兰阴性菌为主,共94株占73.44%;128株病原菌中多药耐药菌72株,占56.25%;大肠埃希菌对亚胺培南和磺胺甲VA唑/甲氧苄啶耐药率较低,克雷伯杆菌对亚胺培南和左氧氟沙星耐药率较低。结论为减少肾盂及输尿管取石术后切口感染率,需积极采取有效的措施,根据药敏实验结果,合理选择抗菌药物,有效控制感染。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and drug resistance of multi-drug resistant bacteria in 121 cases of postoperative incision infection of renal pelvis and ureterolithotomy so as to provide help for prevention of infection and late treatment of infection. Methods from July 2013 to July 2015, 489 cases of renal pelvis and ureterolithotomy were retrospectively analyzed. 121 cases of postoperative incision infection were investigated and analyzed. The specimens were collected for bacterial culture and drug sensitivity test. To analyze the distribution and drug resistance of multidrug resistant bacteria infected after operation. Results among 489 cases of renal pelvis and ureterolithotomy, 121 cases had postoperative incision infection, the infection rate was 24.74%, the infection rate of incision after traditional open incision was the highest, the infection rate was 40.3232 + 121 samples, 128 strains of pathogenic bacteria were isolated. Gram-negative bacteria were the main pathogens, and the resistance rate of Escherichia coli to imipenem and sulfamethoxazole / trimethoprim was low, among which 72 were multidrug resistant strains (56.25%). The resistance of Klebsiella to imipenem and levofloxacin was low. Conclusion in order to reduce the infection rate of incision after renal pelvis and ureterolithotomy, effective measures should be taken. According to the results of drug sensitivity test, antibiotics should be reasonably selected to control infection effectively.
【作者单位】：福建医科大学附属第二医院泌尿外科;
【基金】：福建省自然科学基金资助项目(2012J01372)
【分类号】：R446.5;R699

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