256层螺旋CT对动脉性勃起功能障碍的阴茎血流动力学研究

发布时间：2018-05-01 00:23

本文选题：256层螺旋CT + 动脉性勃起功能障碍　；参考：《昆明医科大学》2017年硕士论文

【摘要】：[目的]研究256层螺旋CT灌流造影对动脉性勃起功能障碍的诊断价值。[方法]对20例无勃起功能障碍成年男性(对照组)及72例诊断为动脉性勃起功能障碍患者(研究组)分别行下腹部256层螺旋CT灌注扫描检查,通过256层螺旋CT灌注成像专用软件重建阴茎血管三维影像,采集阴茎海绵体中段处双侧海绵体组织(感兴趣区5mm2)内动脉的相关灌注参数,如TTP(造影剂密度达到高峰的时间)、BF(每分钟流经100g海绵体组织的血流量单位:ml/100g.min)、BV (每100g海绵体组织的血管床容积单位:ml/100g)等数据,并进行影像学和统计学分析。[结果]对照组双侧海绵体动脉的TTP、BF、BV对比无明显差异(P0.05),CT片显示本组双侧海绵体动脉连续显影较好,重建阴茎血管三维影像可以发现双侧阴茎海绵体动脉呈连续性影像。72例研究组中有63例患者CT片显示单侧阴茎海绵体动脉未显影或显影不连续而另一侧显影较好,9例患者CT片显示双侧阴茎海绵体动脉未显影。63例患者中发生在左侧未显影或显影不连续的占36例,发生在右侧未显影或显影不连续的占27例,利用256层螺旋CT的专用软件重建这63例患者阴茎血管三维影像并进行阴茎海绵体灌注血流动力学研究,发现该组的双侧海绵体动脉灌注参数TTP值、BF值、BV值之间对比有明显差异(P0.05),其中狭窄一侧海绵体动脉灌注参数TTP值、BF值、BV值均较对侧低,且与对照组对比有明显统计学差异(P0.05);剩下的9例患者其CT灌注扫描双侧阴茎海绵体动脉未见显影,重建这9例阴茎血管三维影像发现该组的双侧阴茎海绵体动脉均不能显示。[结论]利用256层螺旋CT灌注重建阴茎血管三维成像,获取相关灌注参数能够很好地研究阴茎血流动力学的变化,同时也能较好地显示阴茎血管和海绵体的病变部位,与其他检查手段相比,具有创伤小,费用低的优点,开创了一种对于动脉性勃起功能障碍诊断的新方法。
[Abstract]:[objective] to study the diagnostic value of 256-slice spiral CT perfusion angiography in arterial erectile dysfunction. [methods] Twenty adult men without erectile dysfunction (control group) and 72 patients diagnosed as arterial erectile dysfunction (study group) were examined with 256-slice spiral CT perfusion scan of lower abdomen, respectively. Three-dimensional images of penile vessels were reconstructed by 256-slice spiral CT perfusion imaging software. The perfusion parameters of bilateral cavernous tissue (5mm ~ 2 mm) were collected at the middle segment of the corpus cavernosum. Data such as TTP (volume of blood flow through 100g cavernous tissue per minute: ml / 100g / min) (volume of vascular bed volume per 100g cavernous tissue: 1 / ml / 100g) and imaging and statistical analysis were performed. [results] in the control group, there was no significant difference in TTPTV-BFFV between the bilateral cavernous arteries and the continuous development of bilateral cavernous arteries was demonstrated by P0.05 CT film. Three-dimensional reconstruction of penis vessels can be found that bilateral cavernous artery in the study group of 72 cases in the study group of 63 patients with CT images of unilateral cavernous artery did not develop or develop discontinuous, the other side of the development is better. Ct findings of bilateral cavernous artery in 9 cases. Of 63 cases, 36 cases occurred in left side without or discontinuous development. There were 27 cases without or discontinuous development on the right side. Three-dimensional images of penile vessels were reconstructed by 256-slice spiral CT software, and hemodynamics of penile cavernous perfusion was studied. It was found that there were significant differences in the TTP value and BF value and BV value of bilateral cavernous artery perfusion parameters in this group (P < 0.05), in which the TTP value and BF value and BV value of cavernous artery perfusion parameter in the narrow side were lower than those in the contralateral side. Compared with the control group, there was a significant difference between the two groups (P 0.05), the remaining 9 patients had no CT perfusion scan of bilateral cavernous artery, and the reconstruction of 9 cases showed that the bilateral cavernous artery could not be displayed. [conclusion] using 256-slice spiral CT perfusion to reconstruct the penile vessels and obtain the relevant perfusion parameters can well study the changes of penile hemodynamics, and at the same time, it can also better display the pathological location of penile vessels and cavernous bodies. Compared with other examination methods, it has the advantages of less trauma and lower cost, thus creating a new method for the diagnosis of arterial erectile dysfunction.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R698.1

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