桂蒲肾清胶囊联合左氧氟沙星治疗尿路感染的临床观察

发布时间：2018-05-18 04:29

本文选题：桂蒲肾清胶囊 + 左氧氟沙星　；参考：《中国药房》2017年33期

【摘要】：目的:观察桂蒲肾清胶囊联合左氧氟沙星治疗尿路感染的临床疗效和安全性。方法:将100例尿路感染患者随机分为观察组(55例)和对照组(45例),观察组患者给予左氧氟沙星片0.1 g,口服,每日2次+桂蒲肾清胶囊1.4 g,口服,每日3次,连用4 d后停用左氧氟沙星片,继续使用桂蒲肾清胶囊治疗3 d。对照组患者给予左氧氟沙星片0.1 g,口服,每日2次,使用时间同观察组+安慰剂胶囊1.4 g,口服,每日3次。两组疗程均为7 d。观察并比较两组患者感染疗效,尿频、尿急、尿痛、尿黄赤各单项评分项(0~6分)人数占比、病原学疗效和不良反应发生情况。结果:治疗后观察组患者感染总有效率(92.7%vs.77.8%)、病原学有效率(72.7%vs.53.3%)显著高于对照组,差异均有统计学意义(P0.05)。治疗前,两组患者尿痛、尿急、尿频、尿黄赤各评分项人数占比比较,差异均无统计学意义(P0.05)。治疗后,两组患者各单项0分项人数占比显著高于同组治疗前,且观察组显著高于对照组;6分项人数占比显著低于同组治疗前,且观察组显著低于对照组,差异均有统计学意义(P0.05)。治疗期间两组患者均未见明显不良反应发生。结论:桂蒲肾清胶囊联合左氧氟沙星治疗尿路感染,可以提高抗感染效果,缓解患者尿路症状,安全性亦较好。
[Abstract]:Objective: to observe the clinical efficacy and safety of Guipu Shenqing capsule combined with levofloxacin in the treatment of urinary tract infection. Methods: 100 patients with urinary tract infection were randomly divided into the observation group (n = 55) and the control group (n = 45). The patients in the observation group were given levofloxacin 0.1 g orally, twice a day, 1. 4 g Guipu Shenqing capsule, 3 times a day. Levofloxacin tablets were stopped for 4 days and continued to be treated with Guipu Shenqing capsule for 3 days. The patients in the control group were given levofloxacin 0.1 g orally twice a day for the same time as the placebo capsule 1.4 g in the observation group three times a day. The course of treatment in both groups was 7 days. The number of patients with infection, frequency of urination, urination frequency, urinal pain, urinary yellow erythema score of 0 ~ 6) were observed and compared between the two groups. The etiological efficacy and adverse reactions were observed and compared between the two groups. Results: the total effective rate of infection in observation group was 92.7vs.77.8 and the effective rate of etiology was 72.7vs.53.3It was significantly higher than that of control group (P 0.05). Before treatment, there was no significant difference in the number of patients with urinary pain, urinal urgency, frequency of urination, and urinary yellow red score between the two groups (P 0.05). After treatment, the percentage of 0 item in each item in the two groups was significantly higher than that before treatment in the same group, and the proportion of the observation group was significantly higher than that in the control group (P < 0.05), and the proportion of the observation group was significantly lower than that in the control group. The difference was statistically significant (P 0.05). No significant adverse reactions occurred in both groups during treatment. Conclusion: Guipu Shenqing capsule combined with levofloxacin in the treatment of urinary tract infection can improve the effect of anti-infection and relieve the symptoms of urinary tract.
【作者单位】：重庆市中医院;
【分类号】：R691.3

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