TURBT质量对NMIBC治疗的影响

发布时间：2018-05-26 13:29

本文选题：非肌层浸润性膀胱癌 + 初次随访复发率(recurrence　；参考：《中南大学》2014年硕士论文

【摘要】：目的：对比非肌层侵润性膀胱癌电切术后标本中有无肌层对早期复发率的影响以及手术经验对标本质量以及手术并发症的影响。方法：回顾性分析2008-2012年间我院泌尿外科初诊及复发非肌层浸润性膀胱癌(non-muscle invasive bladder cancer NMIBC)并行经尿道膀胱肿瘤电切(transurethral resection of bladder tumour TURBT)术的患者共116例,依据术后病理结果标本中有无肌层组织进行分组,其中标本中含有肌层的患者56例,设为A组；无肌层的患者60例,设为B组；统计并分析两组患者的基本特征、肿瘤基本特征、患者手术医生的经验、术后并发症,术后初次随访膀胱镜检复发率。结果：两组患者肿瘤基本特征,包括肿瘤分期(p=0.8770.05)；肿瘤分级(p=0.9310.05),差异无统计学意义；术后并发症,包括膀胱出血(p=0.0360.05)差异有统计学意义,膀胱穿孔(p=0.2990.05)差异无统计学意义；术后肿瘤早期复发率有统计学差异(p=0.0330.05)。即A组患者复发率低于B组患者复发率。手术医生组成(p=0.0000.05)差异有统计学意义。结论：TURBT术后标本中无肌层组织是NMIBC早期复发的危险因素,手术经验影响标本的质量和术后并发症的发生率。
[Abstract]:Objective: to compare the influence of muscle layer on the early recurrence rate of non-muscular invasive bladder cancer after electroresection, and the effect of surgical experience on the quality and complications of the operation. Methods: a retrospective analysis of 116 patients with non-muscle invasive bladder cancer NMIBC) and transurethral resection of bladder tumour TURBT) was performed in our hospital from 2008 to 2012. According to the pathological results, 56 patients with muscular layer were divided into group A, 60 patients without muscle layer were divided into group B, and the basic characteristics of the two groups were analyzed. The basic features of the tumor, the experience of the surgeon, the postoperative complications, and the recurrence rate of the first follow-up of cystoscopy. Results: there was no significant difference in the basic characteristics of tumor between the two groups, including tumor staging (p0.9310.05), postoperative complications, including bladder hemorrhage (p0.0360.05), and bladder perforation (p0.2990.05). There was statistical difference in the early recurrence rate of tumor after operation. The recurrence rate of group A was lower than that of group B. There was significant difference in the composition of surgical doctors (0.0000.05). Conclusion the absence of muscular tissue is a risk factor for the early recurrence of NMIBC. Surgical experience affects the quality of the specimen and the incidence of postoperative complications.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.14

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