维持性腹膜透析患者颈动脉钙化的相关因素分析

发布时间：2018-06-16 06:54

  本文选题：腹膜透析 + 颈动脉钙化　； 参考：《重庆医科大学学报》2017年02期

【摘要】：目的:探讨维持性腹膜透析患者颈动脉钙化的相关危险因素。方法:入选绵阳市中心医院腹膜透析室稳定接受规律腹膜透析的患者100人,按照颈动脉是否钙化分为颈动脉钙化组(55例),颈动脉正常组(45例)。收集患者临床资料,评估残余肾功能和透析充分性,采用彩超检查评估颈动脉有无钙化。用二元logistics回归法分析颈动脉钙化的独立危险因素。结果:2组患者比较:颈动脉钙化组较颈动脉正常组年龄(42.36±8.79 vs.34.93±9.60)岁、空腹血糖(6.91±0.44 vs.6.66±0.30)mmol/L、钙磷乘积(3.98±0.40 vs.3.82±0.30)mmol/L、甲状旁腺激素(parathyroid hormone,PTH)(270.72±30.24 vs.260.23±11.05)ng/L增加(P0.05),而残余肾功能(2.25±0.74 vs.5.14±1.07)m L/min、总肌酐清除率(creatinine clearance rate,Ccr)(59.92±3.94 vs.66.11±7.01)L/(周·1.73 m~2)、残余肾Ccr(19.66±2.85 vs.25.07±6.53)L/(周·1.73 m~2)、总尿素清除指数(urea clearance index,Kt/V)(4.06±0.51 vs.4.46±0.39)、残肾Kt/V(1.12±0.30 vs.1.45±0.28)较颈动脉正常组降低(P0.05)。logistic回归分析显示:透析龄(OR=1.218,P=0.039)、钙磷乘积(OR=70.403,P=0.037)、残余肾功能(OR=0.030,P=0.001)、残肾Ccr(OR=0.692,P=0.015)是颈动脉钙化的影响因素。结论:行规律腹膜透析患者的颈动脉钙化发生率较高,透析龄长、高钙磷乘积和低残余肾功能是腹膜透析患者发生颈动脉钙化的独立危险因素。
[Abstract]:Objective: to investigate the risk factors of carotid artery calcification in maintenance peritoneal dialysis patients. Methods: 100 patients who received regular peritoneal dialysis in peritoneal dialysis room of Mianyang central hospital were divided into carotid artery calcification group (55 cases) and normal carotid artery group (45 cases) according to whether the carotid artery was calcified or not. Clinical data were collected to evaluate residual renal function and dialysis adequacy, and carotid artery calcification was evaluated by color Doppler ultrasonography. The independent risk factors of carotid artery calcification were analyzed by binary logistics regression. Results the age of carotid calcification group was 42.36 卤8.79 vs.34.93 卤9.60 years old than that of normal carotid artery group. 绌鸿吂琛，

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