慢性肾脏病患者合并高血压的影响因素研究

发布时间：2018-09-13 08:31

【摘要】：目的了解慢性肾脏病(CKD)患者合并高血压情况,并探讨其影响因素。方法选取2013年3—7月,在新疆医科大学第一附属医院肾病科接受住院治疗的CKD患者228例。根据合并高血压情况,将其分为非高血压组(n=92)和高血压组(n=136)。比较并分析两组一般资料和各项实验室检测指标,探讨CKD患者合并高血压的影响因素。结果 (1)228例CKD患者的高血压合并率为59.6%(136/228)。高血压组和非高血压组病因、合并症中的糖尿病和心血管疾病、病情分期、平均年龄、收缩压、舒张压、尿酸及肾小球滤过率(GFR)比较,差异有统计学意义(P0.05);而性别、民族、文化程度、吸烟史、合并症中的呼吸系统疾病、平均病程、24 h尿蛋白定量、三酰甘油、胆固醇及BMI比较,差异无统计学意义(P0.05)。(2)136例合并高血压患者的高血压治疗率为96.3%(131/136),血压控制率为45.6%(62/136)。不同病情分期患者的血压控制率比较,差异无统计学意义(P0.05)。(3)Logistic回归分析显示,年龄、24 h尿蛋白定量及GFR对CKD患者合并高血压的影响有统计学意义(P0.05)。结论 CKD患者的高血压合并率较高,治疗率较高,但控制率较差;年龄、24 h尿蛋白定量及GFR是其影响因素。
[Abstract]:Objective to investigate the prevalence of hypertension in patients with chronic kidney disease (CKD) and explore its influencing factors. Methods 228 CKD patients who were hospitalized in the Renal Department of the first affiliated Hospital of Xinjiang Medical University from March to July 2013 were selected. According to the condition of complicated hypertension, it was divided into two groups: non-hypertension group (n-92) and hypertension group (n-136). To compare and analyze the two groups of general data and various laboratory indicators to explore the influencing factors of hypertension in patients with CKD. Results (1) the incidence of hypertension in 228 patients with CKD was 59.6% (136 / 228). There were significant differences in etiology, diabetes and cardiovascular disease, stage of disease, mean age, systolic blood pressure, diastolic blood pressure, uric acid and glomerular filtration rate (GFR) between hypertension group and non-hypertension group (P0.05). Education, smoking history, respiratory diseases in complications, average duration of 24 h urinary protein quantification, triacylglycerol, cholesterol and BMI, There was no significant difference (P0.05). (2). The hypertension treatment rate was 96.3% (131 / 136), and the blood pressure control rate was 45.6% (62 / 136). There was no significant difference in blood pressure control rate between patients with different stages of the disease (P0.05). (3) Logistic regression analysis showed that the age of 24 hours urine protein quantitative and GFR on the CKD patients with hypertension had statistical significance (P0.05). Conclusion the incidence of hypertension in patients with CKD is higher, the rate of treatment is higher, but the control rate is poor, the quantitative analysis of urinary protein at 24 h and GFR are the influencing factors.
【作者单位】：新疆医科大学第一附属医院肾病科;
【基金】：新疆维吾尔自治区心血管病研究重点实验室开放课题项目(XJDX0903-2011-06)
【分类号】：R692;R544.1

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