以血清电解质和尿常规为基础的高校男性青年教师上尿路结石风险方程的建立

发布时间：2018-10-07 20:53

【摘要】：目的研究血清电解质及尿比重、p H值与上尿路结石的相关性,初步探讨高校男性青年教师结石的发病相关因素。方法回顾性分析2006年7月-2014年10月因上尿路结石住院治疗的153例高校男性青年教师临床资料,另选206例健康体检资料作为对照,比较两者血清钾(K)、钠(Na)、氯(Cl)、钙(Ca)、二氧化碳结合力(CO2-CP)、尿比重(SG)和p H值的差异,并构建Logistic回归方程。结果与对照组相比,结石组血清钾和尿p H值明显偏低,而血清钠、氯、钙和尿比重明显偏高。经过Logistic回归后得到高校男性青年教师上尿路结石的风险方程Y=exp(-115.05-2.53×K+0.29×Na+5.20×Ca-1.14×p H+74.69×SG)/[1+exp(-115.05-2.53×K+0.29×Na+5.20×Ca-1.14×p H+74.69×SG)]。结论血清钾、钠、钙、p H值和尿比重可能参与上尿路结石的发生过程。风险方程的应用有助于该疾病的个体化防治。
[Abstract]:Objective to study the correlation between serum electrolytes and urine specific gravity and upper urinary tract stones, and to explore the related factors of male young teachers' calculi in colleges and universities. Methods the clinical data of 153 male young college teachers who were hospitalized for upper urinary calculi from July 2006 to October 2014 were retrospectively analyzed. The difference of serum potassium (K), sodium (Na), chlorine (Cl), calcium (Ca), carbon dioxide binding capacity (CO2-CP) urine specific gravity (SG) and pH between the two groups was compared and Logistic regression equation was established. Results compared with the control group, the serum potassium and urine pH values in the stone group were significantly lower, while the serum sodium, chlorine, calcium and urine specific gravity were higher than those in the control group. Y=exp (-115.05-2.53 脳 K 0.29 脳 Na 5.20 脳 Ca-1.14 脳 pH 74.69 脳 SG) / [1 exp (-115.05-2.53 脳 K 0.29 脳 Ca-1.14 脳 pH 74.69 脳 SG)] was obtained by Logistic regression. Conclusion Serum potassium, sodium, calcium pH and urinary specific gravity may play an important role in the development of upper urinary calculi. The application of the risk equation is helpful to the individualized prevention and treatment of the disease.
【作者单位】：解放军252医院泌尿外科;河北农业大学艺术学院;
【基金】：解放军252医院院管课题基金资助项目[(YY2012-12)和(2014252YY01)]
【分类号】：R691.4

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