肾结石患者术后泌尿系感染的病原学特点及危险因素研究
发布时间：2018-10-08 10:45
【摘要】：目的研究肾结石患者术后泌尿系感染的病原学特点及危险因素。方法回顾性分析2013年5月-2016年5月医院收治的494例行肾结石手术患者临床资料,统计患者术后泌尿系统感染率,分析感染病原学特点及致病菌耐药性,并分析相关危险因素。结果 494例肾结石患者术后泌尿系统感染74例,感染率为14.98%,74例感染患者共检出病原菌101株,其中革兰阳性菌31株,占30.69%,革兰阴性菌63株,占62.38%,真菌7株,占6.93%;大肠埃希菌与肺炎克雷伯菌对头孢吡肟、哌拉西林-他唑巴坦、亚胺培南及阿米卡星具有较强的耐药性,对环丙沙星、磺胺甲VA唑/甲氧倫啶等的敏感性较高,粪肠球菌与屎肠球菌对青霉素、红霉素、阿奇霉素等有较强的耐药性,对万古霉素、亚胺培南及米诺环素等抗菌药物的敏感性较高;年龄≥60岁、术前尿WBC≥2个/高倍视野及住院时间≥10d是肾结石患者术后发生泌尿系感染的相关危险因素;Logistic回归分析显示年龄、术前尿WBC及住院时间为肾结石患者术后发生泌尿系感染的独立危险因素(P0.05)。结论应针对具有肾结石危险因素患者,加强术后防治措施,以减少泌尿系统感染发生率。
[Abstract]:Objective to study the etiological characteristics and risk factors of urinary tract infection in patients with renal calculi after operation. Methods the clinical data of 494 patients with renal calculi treated in our hospital from May 2013 to May 2016 were analyzed retrospectively. The infection rate of urinary system, the pathogenic characteristics, the resistance of pathogenic bacteria and the risk factors were analyzed. Results there were 74 cases of urinary tract infection after operation in 494 patients with renal calculi, and the infection rate was 14.98%. A total of 101 strains of pathogenic bacteria were detected, including 31 strains of Gram-positive bacteria (30.69%), 63 strains of Gram-negative bacteria (62.38%) and 7 strains of fungi. Escherichia coli and Klebsiella pneumoniae were highly resistant to cefepime, piperacillin-tazobactam, imipenem and amikacin, and had higher sensitivity to ciprofloxacin, sulfamethoxazole / methoxyrenidine, etc. Enterococcus faecalis and Enterococcus faecium have strong resistance to penicillin, erythromycin and azithromycin, and have higher sensitivity to vancomycin, imipenem and minocycline. Preoperative urinary WBC 鈮，
本文编号：2256472
[Abstract]:Objective to study the etiological characteristics and risk factors of urinary tract infection in patients with renal calculi after operation. Methods the clinical data of 494 patients with renal calculi treated in our hospital from May 2013 to May 2016 were analyzed retrospectively. The infection rate of urinary system, the pathogenic characteristics, the resistance of pathogenic bacteria and the risk factors were analyzed. Results there were 74 cases of urinary tract infection after operation in 494 patients with renal calculi, and the infection rate was 14.98%. A total of 101 strains of pathogenic bacteria were detected, including 31 strains of Gram-positive bacteria (30.69%), 63 strains of Gram-negative bacteria (62.38%) and 7 strains of fungi. Escherichia coli and Klebsiella pneumoniae were highly resistant to cefepime, piperacillin-tazobactam, imipenem and amikacin, and had higher sensitivity to ciprofloxacin, sulfamethoxazole / methoxyrenidine, etc. Enterococcus faecalis and Enterococcus faecium have strong resistance to penicillin, erythromycin and azithromycin, and have higher sensitivity to vancomycin, imipenem and minocycline. Preoperative urinary WBC 鈮，
本文编号：2256472
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