输尿管肾源性腺瘤合并肾脏结核1例并文献复习

发布时间：2018-10-13 09:00

【摘要】：目的探讨输尿管肾源性腺瘤(nephrogenic adenoma,NA)的临床病理学和免疫表型特征。方法回顾性分析1例输尿管NA合并肾脏结核的临床资料及病理学特征,对其行HE及免疫组化En Vision法染色,并复习相关文献。结果患者男性,18岁。大体上输尿管腔内见狭窄区;镜下见黏膜下增生腺体形成小管状、乳头状结构,管腔大小形状不一,被覆单层立方上皮,黏膜下见慢性炎细胞浸润;肾脏结核改变。免疫表型:AMACR(P504s)(+);CK7(弱+);CK34βE12(局灶+);CD10、CK20、Villin、vimentin(-)。结论输尿管NA是非常少见的泌尿系统病变,需与息肉、移行细胞癌及腺癌鉴别,掌握其组织形态特征及免疫表型是正确诊断的关键。
[Abstract]:Objective to investigate the clinicopathological and immunophenotypic features of ureteral renal adenoma (nephrogenic adenoma,NA). Methods A case of ureteral NA complicated with renal tuberculosis was retrospectively analyzed. HE and immunohistochemical En Vision staining were performed. Results the patient was 18 years old. In general, the stricture area was seen in ureteral lumen. Under the microscope, there were small tubules, papillary structure, different shape of lumen, single layer cubic epithelium, chronic inflammatory cell infiltration in submucous membrane, and the change of renal tuberculosis. Immunophenotype: AMACR (P504s) (); CK7 (weak); CK34 尾 E12 (focal); CD10,CK20,Villin,vimentin (-). Conclusion Ureteral NA is a rare urinary system disease. It is necessary to differentiate ureteral NA from polyps, transitional cell carcinoma and adenocarcinoma. It is the key to correct diagnosis to master the histological features and immunophenotypes of ureteral NA.
【作者单位】： 山东省聊城市第二人民医院病理科;
【分类号】：R527.1;R737.13
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本文编号：2268025