心踝血管指数对腹膜透析患者动脉硬化的预测价值及相关影响因素
发布时间:2018-10-24 14:16
【摘要】:目的评估心踝血管指数在腹膜透析患者动脉硬化中的应用价值及相关影响因素。方法选择95例维持性腹膜透析患者,收集患者的基本信息和实验室指标,同时测定患者的心踝血管指数(CAVI)。根据CAVI是否升高分为高CAVI组(CAVI≥9)和正常CAVI组(CAVI9)。结果高CAVI组CAVI(9.85±0.73)明显高于正常CAVI组(7.67±0.81),高CAVI组年龄(54.64±5.68岁)、透析时间(48.32±30.43月)、脉压(57.41±12.43 mm Hg)、血清矫正钙(2.52±0.28 mmol/L)、血磷(2.22±0.66 mmol/L)、钙磷乘积(5.59±1.70)、空腹血糖(6.02±1.83 mmol/L)明显高于正常CAVI组,血红蛋白(83.96±20.53 g/L)、血白蛋白(32.40±5.22 g/L)明显低于正常CAVI组。Spearman相关分析显示腹膜透析患者CAVI与年龄、透析时间、脉压、血清矫正钙、血磷、钙磷乘积、空腹血糖、高敏C反应蛋白呈正相关(r值分别为0.520、0.260、0.244、0.347、0.231、0.338、0.225、0.298,P均0.05),与血白蛋白、25-羟维生素D呈负相关(r值分别为-0.335、-0.222,P均0.05);多元线性回归分析显示年龄、血白蛋白是腹膜透析患者CAVI的独立危险因素。结论心踝血管指数可以作为评价腹膜透析患者动脉硬化的无创检测指标,早期检测心踝血管指数、改善营养状况可以降低腹膜透析患者动脉硬化发生风险,减少心血管疾病的发生,改善预后。
[Abstract]:Objective to evaluate the clinical value of malleolus index in peritoneal dialysis patients with arteriosclerosis. Methods 95 patients with maintenance peritoneal dialysis were selected and their basic information and laboratory parameters were collected. Meanwhile, the cardiac and ankle vascular index (CAVI).) was measured. According to whether CAVI increased or not, high CAVI group (CAVI 鈮,
本文编号:2291642
[Abstract]:Objective to evaluate the clinical value of malleolus index in peritoneal dialysis patients with arteriosclerosis. Methods 95 patients with maintenance peritoneal dialysis were selected and their basic information and laboratory parameters were collected. Meanwhile, the cardiac and ankle vascular index (CAVI).) was measured. According to whether CAVI increased or not, high CAVI group (CAVI 鈮,
本文编号:2291642
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