男性不育患者生殖道溶脲脲原体感染对精液质量的影响

发布时间：2018-11-07 13:54

【摘要】：目的探讨男性不育患者生殖道溶脲脲原体感染对精液质量的影响。方法选取2016年8月-2017年3月医院所收治的168例男性不育患者作为不育组,另选同期成年男性志愿者150例作为已育组。比较分析两组生殖道感染溶脲脲原体情况,生殖道溶脲脲原体感染与非感染男性不育患者精液参数、精子活动能力及α-葡萄糖苷酶水平。结果不育组生殖道溶脲脲原体感染率35.12%显著高于已育组24.67%(P0.05)。与溶脲脲原体阴性相比,溶脲脲原体阳性患者精子密度(85.58±9.74)×10~6/mL,精子活率(45.74±5.22)%,精子活力(39.55±4.36)%均明显降低,差异均具有统计学意义(P均0.05);溶脲脲原体阳性患者精子平均曲线运动速度(34.08±4.75)μm/s,平均直线运动速度(23.40±3.02)μm/s,平均路径速度(27.08±3.57)μm/s,平均移动角度(47.81±5.83)°,平均鞭打频率(5.03±0.59)%与溶脲脲原体阴性相比均明显降低,差异均具有统计学意义(P均0.05);溶脲脲原体阳性患者α-葡萄糖苷酶水平处于异常的比率为50.85%明显高于溶脲脲原体阴性患者29.36%(P均0.05)。结论在男性不育中生殖道溶脲脲原体感染相对较高,并对精液参数和精子活动能力造成一定的影响,从而导致精液质量的大幅度降低,进而引起男性不育。
[Abstract]:Objective to investigate the effect of Ureaplasma Urealyticum infection on semen quality in male infertile patients. Methods 168 male infertile patients admitted in our hospital from August 2016 to March 2017 were selected as infertility group, and 150 adult male volunteers were selected as fertile group. The semen parameters, sperm motility and 伪-glucosidase level of male infertile men infected with Ureaplasma Urealyticum in reproductive tract were compared and analyzed. Results the infection rate of Ureaplasma Urealyticum in reproductive tract in infertile group was 35.12%, significantly higher than that in fertile group (24.67%) (P0.05). Compared with Ureaplasma Urealyticum negative, the sperm density (85.58 卤9.74) 脳 10 ~ (-6) / mL, sperm motility (45.74 卤5.22)% and sperm motility (39.55 卤4.36)% were significantly decreased in Ureaplasma Urealyticum positive patients. The difference was statistically significant (P 0.05). The average curve velocity of sperm motion was (34.08 卤4.75) 渭 m / s, the average linear velocity was (23.40 卤3.02) 渭 m / s, and the average path velocity was (27.08 卤3.57) 渭 m / s in Ureaplasma Urealyticum positive patients. The mean movement angle (47.81 卤5.83) 掳and the average whipping frequency (5.03 卤0.59)% were significantly lower than those of Ureaplasma Urealyticum negative (P 0.05). The rate of abnormal level of 伪 -glucosidase in Ureaplasma Urealyticum positive patients was 50.85%, and 29.36% in Ureaplasma Urealyticum negative patients (P 0.05). Conclusion Ureaplasma Urealyticum infection in reproductive tract is relatively high in male infertility, which has a certain effect on semen parameters and sperm motility, which leads to a large decrease in semen quality, and then causes male infertility.
【作者单位】：贵州省遵义医学院附属医院生殖中心;
【基金】：贵州省科学技术基金资助项目黔科合LH字(2014)7569
【分类号】：R698.2

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