针挑疗法联合左卡尼汀治疗男性不育弱精子症的临床观察

发布时间：2019-01-05 01:34

【摘要】：目的：观察联合应用针挑疗法和口服左卡尼汀治疗男性不育弱精子症的治疗效果，探索一种新的临床治疗弱精子症的中西医结合疗方法。方法：选取2012年6月～2013年12月期间，在我院新医针挑科不孕不育门诊就诊的弱精子症患者120例，运用数表法随机分为针挑疗法组、左卡尼汀组和针药联合组。针挑治疗每周一次，左卡尼汀口服液为餐后口服，一次1支（10ml），每日3次，治疗周期3个月。分别记录患者治疗前后精子密度、活率、快速前向运动精子百分比、前向运动精子百分比等精液常规参数，将结果进行统计学分析。结果：研究中共脱落病例9例，脱落率7.5%（9/120）。三种不同治疗方法各自进行组内比较显示，各项精液常规参较治疗前均有显著的提升，治疗前后的差异具有明显的统计学意义（P0.05）。对治疗之后的结果进行组间比较发现，针挑疗法组和左卡尼汀组各项参数之间的差异没有统计学意义（P0.05）；针药联合组与其他两组比较，快速前向运动精子百分比和前向运动精子百分比升高更明显，并且差异都有统计学意义（P0.05）；在改善精子密度方面，针药结合组较其他两组升高更多，但与针挑疗法组比较，差异没有统计学意义（t=-1.71，P=0.090.05）；与左卡尼汀组比较，差异显著（t=-2.26，P=0.030.05）；在改善精子活率方面，治疗后三种疗法组间相互比较，均无统计学意义（P0.05）。结论：单独应用针挑疗法或口服左卡尼汀治疗，，均能显著提高快速前向运动精子百分比、前向运动精子百分比，有利于提高女方妊娠率，但二者在改善精液质量方面无明显差异。针挑疗法联合口服左卡尼汀是一种新的中西医结合治疗弱精子症的方法，其治疗效果优于单独应用左卡尼汀或针挑疗法，并且该方法操作简便，易于掌握，取材方便，安全有效，值得在临床上应用及推广。
[Abstract]:Objective: to observe the therapeutic effect of combined acupuncture therapy and oral levacarnitine in the treatment of male infertility and asthenospermia, and to explore a new method of integrated traditional Chinese and western medicine for the treatment of asthenospermia. Methods: from June 2012 to December 2013, 120 patients with asthenospermia were selected and randomly divided into three groups: acupuncture group, left carnitine group and combined acupuncture and medicine group. Acupuncture therapy was done once a week, levacanitine oral solution was taken orally after meal, one dose (10ml), 3 times a day, the treatment period was 3 months. Sperm density, motility rate, fast forward motility sperm percentage and forward motility sperm percentage were recorded before and after treatment, and the results were analyzed statistically. Results: 9 cases of shedding cases were studied, the exfoliation rate was 7.5% (9 / 120). The results showed that the semen routine parameters were significantly improved before and after treatment, and the difference before and after treatment was statistically significant (P0.05). After the treatment of the results of comparison between the group found that the acupuncture group and the left carnitine group between the parameters of the difference was not statistically significant (P0.05); Compared with the other two groups, the percentage of fast forward motility sperm and the percentage of forward motile sperm increased significantly in the acupuncture and medicine combination group, and the difference was statistically significant (P0.05). In improving the sperm density, the acupuncture and drug combination group increased more than the other two groups, but there was no significant difference compared with the acupuncture group (t = 1.71, P < 0.090.05). Compared with levocarnitine group, the difference was significant (t _ (2.26) P _ (0.030.05), in improving sperm motility, there was no significant difference between the three treatment groups after treatment (P0.05). Conclusion: acupuncture alone or oral L-carnitine therapy can significantly increase the percentage of fast forward motility sperm and improve the pregnancy rate of women. But there was no significant difference between them in improving semen quality. Acupuncture therapy combined with oral levacarnitine is a new method of treating asthenospermia with combination of traditional Chinese and western medicine, and its therapeutic effect is better than that of single application of left carnitine or acupuncture therapy, and the method is simple, easy to grasp and easy to take materials. Safe and effective, worthy of clinical application and promotion.
【学位授予单位】：暨南大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R698.2

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