膀胱鳞癌与浸润性尿路上皮癌的临床对比研究

发布时间：2019-02-22 14:42

【摘要】：目的：探讨膀胱鳞癌与浸润性尿路上皮癌在发病特点、治疗及预后的异同点，增强对膀胱鳞癌的进一步认识，提高诊治水平。方法：回顾性分析我院2011年1月至2014年1月收治的膀胱鳞癌9例、浸润性尿路上皮癌32例的临床资料，并参考国内外相关文献进行讨论分析。结果：9例膀胱鳞癌和32例浸润性尿路上皮癌病例中，在血尿为首发症状、疾病进展中发生肉眼血尿不具有统计学意义(P0.05)。而在表现为膀胱刺激症状、尿常规中白细胞明显增多、肿瘤临床分期、肿瘤是否单发的差异具有统计学意义(P 0.05)。膀胱鳞癌组，在手术方式不同情况一年后生存率和一年内死亡率间的差异不具有统计学意义(P0.05)，但整体死亡率较高。结论：膀胱鳞癌在临床上较为少见，症状无特异性，早期诊断较为困难，且浸润性较强，恶性程度很高，确诊时多数患者已发展至晚期，预后与肿瘤的临床分期有紧密的相关性，因此早期的临床诊断和合理的治疗极为重要。
[Abstract]:Objective: to investigate the differences and similarities between bladder squamous cell carcinoma and invasive urothelial carcinoma in the pathogenesis, treatment and prognosis of bladder squamous cell carcinoma, and to enhance the understanding of bladder squamous cell carcinoma and improve the level of diagnosis and treatment. Methods: the clinical data of 9 cases of bladder squamous cell carcinoma and 32 cases of invasive urothelial carcinoma treated in our hospital from January 2011 to January 2014 were analyzed retrospectively. Results: in 9 cases of bladder squamous cell carcinoma and 32 cases of invasive urothelial carcinoma, hematuria was the first symptom. However, there were significant differences in the symptoms of bladder irritation, leukocytosis in urine routine, clinical stage of tumor and whether the tumor was single or not (P 0.05). In the bladder squamous cell carcinoma group, there was no significant difference between the survival rate and the mortality rate within one year in different operation conditions (P0.05), but the overall mortality rate was higher. Conclusion: bladder squamous cell carcinoma is rare in clinic and has no specific symptoms. Early diagnosis is difficult, invasive and malignant. Most of the patients have developed to the late stage by the time of diagnosis. The prognosis is closely related to the clinical stage of the tumor, so early clinical diagnosis and reasonable treatment are very important.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.14

【参考文献】