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前列舒通胶囊联合α-1A受体阻滞剂治疗湿热瘀阻ē型前列腺炎临床观察

发布时间:2019-03-19 20:39
【摘要】:目的观察前列舒通胶囊联合α-1A受体阻滞剂治疗湿热瘀阻III型前列腺炎的临床疗效 方法将121例湿热瘀阻III型前列腺炎患者随机分为治疗组和对照组,分别给予前列舒通胶囊(3粒,,每天3次)+盐酸坦洛新胶囊(0.2mg,每晚1次)和盐酸坦洛新胶囊(0.2mg,每晚1次)治疗,8周后按照美国国立卫生研究所(NIH)制定的前列腺症状评分标准(CPSI)和勃起功能国际问卷(IIEF一5)量化两组患者的症状积分,并观察治疗前后前列腺液中卵磷脂小体白细胞计数和PH值的变化,比较两组患者的临床疗效及其副作用 结果经过8周的治疗,治疗组和对照组的NIH-CPSI评分QOL评分及EPS常规中白细胞数目均有显著下降(P0.01),但治疗组下降的程度均较对照组明显(P0.01);治疗组和对照组的IIEF一5评分均明显上升,治疗组升高程度较对照组明显(P0.01) 结论前列舒通胶囊联合α-1A受体阻滞剂治疗湿热瘀阻型III型前列腺炎比单用α-1A受体阻滞剂疗效明显,值得临床推广
[Abstract]:Objective to observe the clinical efficacy of Qianlieshutong capsule combined with 伪-1A receptor blocker in the treatment of type III prostatitis with damp-heat stasis. Methods 121 cases of type III prostatitis with damp-heat stasis were randomly divided into treatment group and control group. Qianlie Shutong capsule (3 tablets, 3 times a day) and Tanloxin Hydrochloride capsule (0.2 mg, once a night) and Tanloxin Hydrochloride capsule (0.2 mg, once a night) were given, respectively, and were treated with Tanloxin Hydrochloride capsule (0.2 mg, once a night). Eight weeks later, the symptom scores of the two groups were quantified according to the Prostate symptom score Standard (CPSI) developed by the National Institutes of Health (NIH) and the International scale for erectile function (IIEF-5). We also observed the changes of leucocyte count and PH value in prostatic fluid before and after treatment, and compared the clinical efficacy and side effects of the two groups after 8 weeks of treatment. In the treatment group and the control group, the NIH-CPSI score QOL score and the number of white blood cells in the EPS routine were significantly decreased (P0.01), but the degree of decrease in the treatment group was more obvious than that in the control group (P0.01). The IIEF-5 scores in the treatment group and the control group were significantly higher than those in the control group. Conclusion Qianliesutong capsule combined with 伪-1A receptor blocker is more effective than 伪-1A receptor blocker alone in the treatment of type III prostatitis, which is worthy of clinical popularization.
【学位授予单位】:甘肃中医学院
【学位级别】:硕士
【学位授予年份】:2014
【分类号】:R697.33

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