完全无管化经皮肾镜取石术与标准经皮肾镜取石术治疗上尿路结石疗效的Meta分析
发布时间：2019-05-11 04:50
【摘要】：目的:系统评价完全无管化经皮肾镜碎石术与标准经皮肾镜碎石术治疗上尿路结石的疗效方法:通过计算机检索国内外数据库,含Pubmed、The Cochrane Library、Embase、中国生物医学数据库、中国知网、万方数据库,搜索符合要求的随机对照试验和临床对照试验,筛选文献后进行相关数据提取,最后采用Review Manager 5.3软件对数据进行Meta分析。结果:最后11篇文献纳入了研究,其中试验组有439例研究对象,对照组有485例研究对象,Meta分析示:(1)手术总并发症:两组之间差异据有统计学意义,[OR:0.44,95%CI:0.26~0.74,P=0.002](2)术后发热:两组之间差异没有统计学意义,[OR:0.76,95%CI:0.38~1.50,P=0.42](3)血尿:两组之间差异没有统计学意义,[OR:0.60,95%CI:0.14~2.54,P=0.49](4)术后肾周积液:两组间差异没有统计学意义,[OR:0.41,95%CI:0.13~1.29,P=0.13](5)术后辅助排石:两组间差异没有统计学意义,[OR:0.92,95%CI:0.42~2.01,P=0.83](6)术后输血:两组间差异没有统计学意义,[OR:0.69,95%CI:0.35~1.37,P=0.29](7)手术时间:两组间差异没有统计学意义,[WMD:-1.71,95%CI:-3.58~0.16,P=0.07](8)住院时间:两组间差异有统计学意义,[WMD:-2.35,95%CI:-3.20~-1.49,P0.00001](9)术后恢复到正常活动时间:两组间差异没有统计学意义,[WMD:-6.88,95%CI:-14.27~0.50,P=0.07](10)术后肌酐和血红蛋白下降情况:两组间差异没有统计学意义,[WMD:-0.01,95%CI:-0.03~0.01,P=0.48]和[WMD:-0.10,95%CI:-0.22~0.01,P=0.07](11)术后镇痛药的使用情况:两组间差异有统计学意义,[WMD:-6.81,95%CI:-8.40~-5.22,P0.00001]。结论:完全无管化经皮肾镜取石术与标准经皮肾镜取石术治疗上尿路结石方面对比,在住院时间、术后镇痛药使用量、术后总的并发症方面具有优势,差异具有统计学意义;在手术时间、术后恢复到正常活动时间、术后输血、术后发热、术后肾周积液、术后辅助排石、术后肌酐和血红蛋白下降、血尿方面差异无统计学意义,掌握好完全无管化经皮肾镜取石术治疗适应症和严格筛选病人的情况下,值得谨慎推广
[Abstract]:Objective: to systematically evaluate the efficacy of completely non-tubular percutaneous nephrolithotomy and standard transcatheter lithoclast in the treatment of upper urinary calculi. The database at home and abroad, including Pubmed,The Cochrane Library,Embase, Chinese Biomedical Database, was searched by computer. China knowledge network, Wanfang database, search for randomized controlled trials and clinical controlled trials that meet the requirements, screen the literature and extract the relevant data. Finally, Review Manager 5.3 software is used for Meta analysis of the data. Results: the last 11 articles were included in the study, including 439 cases in the experimental group and 485 cases in the control group. Meta analysis showed that: (1) the total complications of the operation: the difference between the two groups was statistically significant. [OR:0.44,95%CI:0.26~0.74,P=0.002] (2) postoperative fever: there was no significant difference between the two groups. [OR:0.76,95%CI:0.38~1.50,] P 鈮，
本文编号：2474258
[Abstract]:Objective: to systematically evaluate the efficacy of completely non-tubular percutaneous nephrolithotomy and standard transcatheter lithoclast in the treatment of upper urinary calculi. The database at home and abroad, including Pubmed,The Cochrane Library,Embase, Chinese Biomedical Database, was searched by computer. China knowledge network, Wanfang database, search for randomized controlled trials and clinical controlled trials that meet the requirements, screen the literature and extract the relevant data. Finally, Review Manager 5.3 software is used for Meta analysis of the data. Results: the last 11 articles were included in the study, including 439 cases in the experimental group and 485 cases in the control group. Meta analysis showed that: (1) the total complications of the operation: the difference between the two groups was statistically significant. [OR:0.44,95%CI:0.26~0.74,P=0.002] (2) postoperative fever: there was no significant difference between the two groups. [OR:0.76,95%CI:0.38~1.50,] P 鈮，
本文编号：2474258
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