泌尿系统感染患者的病原菌分布与耐药性分析

发布时间：2019-06-10 23:41

【摘要】：目的研究医院2013年泌尿系统感染患者病原菌分布及耐药性,为尿路感染的临床诊断和合理用药提供依据。方法收集2013年1-12月医院门诊及住院患者的尿液标本,采用VITEK-32型全自动细菌分析系统对送检标本进行菌株鉴定和药敏试验,并对结果进行分析。结果 2013年1-12月共收集患者尿液标本2 074份,分离出病原菌399株,检出率为19.2%;其中革兰阴性菌224株占56.2%,革兰阳性菌113株占28.3%,真菌62株占15.5%;革兰阴性菌对氨苄西林的耐药性较高,耐药率在73.9%~100.0%,对头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、头孢替坦、厄他培南、亚胺培南等较敏感,耐药率0~17.1%;革兰阳性菌对青霉素G、氨苄西林/舒巴坦、头孢替坦、氨曲南、克林霉素等高度耐药,耐药率96.00%,对利奈唑胺、万古霉素、替加环素高度敏感,耐药率1.30%;真菌对抗真菌药物敏感性相对较好。结论泌尿系统感染病原菌以革兰阴性菌为主,革兰阴性菌和革兰阳性菌的耐药性较严重,临床治疗应尽早进行病原学检测和药敏试验,减少经验性用药,合理选用抗菌药物,有效控制泌尿系统感染。
[Abstract]:Objective to study the distribution and drug resistance of pathogenic bacteria in patients with urinary tract infection in hospital in 2013, and to provide evidence for clinical diagnosis and rational drug use of urinary tract infection. Methods urine samples from outpatients and inpatients in hospital from January to December 2013 were collected. The strains were identified and tested by VITEK- 32 automatic bacterial analysis system, and the results were analyzed. Results A total of 2074 urine samples were collected from patients from January to December 2013, 399 strains of pathogenic bacteria were isolated, the detection rate was 19.2%, 224 strains of Gram-negative bacteria accounted for 56.2%, 113 strains of Gram-positive bacteria accounted for 28.3%, 62 strains of fungi accounted for 15.5%. Gram-negative bacteria were highly resistant to ampicillin, the resistance rate was 73.9% 鈮，

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