3例阴茎透明细胞癌:一种与HPV相关的鳞状细胞癌变异亚型的报道
发布时间：2019-08-03 17:56
【摘要】：正目前文献报道的阴茎透明细胞癌起源于皮肤附属器的腺体。作者介绍了3例形态学独特的阴茎肿瘤,该肿瘤具有明显的透明细胞特点,但并非起源于阴茎皮肤,而是起源于龟头表面鳞状上皮的黏膜组织。作者对其临床及病理学特征进行分析。免疫组化检测GATA3及p16的表达。采用原位杂交法检测3例阴茎透明细胞癌的HPV表达情况,其中1例全组织切片进行聚合酶链反应。患者年龄分别为52、88
[Abstract]:Clear cell carcinoma of the penis, as reported in the literature, originates from the gland of the skin appendage. Three cases of penile tumors with unique morphology were introduced. The tumor has obvious clear cell characteristics, but does not originate from penile skin, but from the mucous tissue of scaly epithelial tissue on the surface of glans. The clinical and pathological features were analyzed. The expression of GATA3 and p16 was detected by immunohistochemistry. The expression of HPV in 3 cases of clear cell carcinoma of penis was detected by in situ hybridization, and 1 case of whole tissue section was detected by polymerase chain reaction (PCR). The ages of the patients were 52 and 88 respectively.
【作者单位】： 浙江省绍兴市人民医院病理科;解放军307医院病理科;
【分类号】：R737.27
[Abstract]:Clear cell carcinoma of the penis, as reported in the literature, originates from the gland of the skin appendage. Three cases of penile tumors with unique morphology were introduced. The tumor has obvious clear cell characteristics, but does not originate from penile skin, but from the mucous tissue of scaly epithelial tissue on the surface of glans. The clinical and pathological features were analyzed. The expression of GATA3 and p16 was detected by immunohistochemistry. The expression of HPV in 3 cases of clear cell carcinoma of penis was detected by in situ hybridization, and 1 case of whole tissue section was detected by polymerase chain reaction (PCR). The ages of the patients were 52 and 88 respectively.
【作者单位】： 浙江省绍兴市人民医院病理科;解放军307医院病理科;
【分类号】：R737.27
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1 向梅;;透明细胞癌的手术治疗[J];国外医学.妇产科学分册;2006年03期
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