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后腹腔镜保留肾单位手术治疗老年T1a期肾癌的疗效

发布时间:2019-08-15 08:55
【摘要】:目的分析老年T1a期肾癌患者进行后腹腔镜保留肾单位肾部分切除术(LNSS)的有效性和安全性。方法老年T1a期肾癌患者103例依据手术方法不同分为两组:LNSS组48例,平均年龄(65.1±3.0)岁;后腹腔镜根治性肾切除术(LRN)组55例,平均年龄(64.5±3.1)岁;比较两组手术时间、术中出血量和住院时间,并在术前、术后1 d、术后6、12个月取血测量血清肌酐。随访12~78个月,获得患者的远期疗效。结果LNSS组手术时间、术中出血量和住院时间均显著大于LRN组(P0.01);两组围术期并发症(肺炎、脑梗死、肺栓塞)比率差异无统计学意义(P0.05);两组术前、术后1 d以及术后6个月和12个月的血清肌酐水平比较差异均无统计学意义(均P0.05);两组远期疗效比较差异无统计学意义(P0.05)。结论 LNSS保留了患者肾功能,临床上对老龄局限性小肾癌患者安全有效。
[Abstract]:Objective to analyze the efficacy and safety of retrolaparoscopic partial renal unit renal resection (LNSS) in elderly patients with stage T1a renal carcinoma. Methods according to the different surgical methods, 103 elderly patients with stage T1a renal cell carcinoma were divided into two groups: LNSS group (n = 48, mean age (65.1 卤3.0) years), retrolaparoscopic radical nephroresection group (n = 55, mean age (64.5 卤3.1) years), operation time, intraoperative blood loss and hospitalization time, and serum creatinine was measured before operation, 1 day after operation and 6 months after operation. The patients were followed up for 12 to 78 months to obtain the long-term curative effect. Results the operation time, intraoperative blood loss and hospitalization time in LNSS group were significantly higher than those in LRN group (P 0.01). There was no significant difference in perioperative complications (pneumonia, cerebral infarction, pulmonary embolism) between the two groups (P 0.05). There was no significant difference in serum creatinine level between the two groups before operation, 1 day after operation and 6 months and 12 months after operation (both P 0.05). There was no significant difference in long-term curative effect between the two groups (P 0.05). Conclusion LNSS preserves the renal function of the patients and is safe and effective in the elderly patients with localized small renal cell carcinoma.
【作者单位】: 吉林大学第一医院泌尿外二科;
【分类号】:R737.11

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