单侧上尿路梗阻解除前后肾皮质厚度与肾小球滤过率的关系
发布时间:2019-08-24 19:40
【摘要】:目的探讨单侧上尿路梗阻解除前后肾皮质厚度(RCT)与肾小球滤过率(GFR)的关系。方法选取2015年7月-2016年6月该院泌尿外科收治的63例上泌尿道梗阻患者为研究对象。其中,男34例,女29例,年龄22~73(52.21±11.56)岁;手术方式:输尿管镜碎石+取石术24例,一期经皮肾造瘘+二期经皮肾镜取石术(PCNL)21例,一期PCNL 18例。采用腹部增强CT、单光子发射计算机断层(SPECT)扫描分别测量RCT和GFR,根据术前患肾GFR情况分为3组:A组(中度肾损害,15.0 ml/min≤GFR30.0 ml/min)、B组(重度肾损害,7.5 ml/min≤GFR15.0 ml/min)、C组(极重度肾损害,GFR7.5 ml/min),比较3组的手术前后的GFR变化。采用简单线性相关分析A和B组患者术前RCT与各指标的相关性。结果 9例患者因肾积水严重未测量RCT,患者的术前RCT10 mm 20例,5~10 mm 23例,5 mm 11例,平均值为(10.75±4.91)mm。A组术前RCT明显高于B组,差异有统计学意义(P0.05)。3组患者术后1和9个月的GFR均明显高于同组术前,差异均有统计学意义(P0.05)。A组术后1和9个月的GFR均明显高于另外两组,B组术后9个月的GFR明显高于C组,差异均有统计学意义(P0.05),但术后1个月B组和C组的GFR差异无统计学意义(P0.05)。B组术后1个月的GFR恢复值明显低于另外两组,差异有统计学意义(P0.05),3组术后9个月的GFR恢复值比较差异无统计学意义(P0.05)。术前RCT与术前GFR(r=0.613)、术后1个月GFR(r=0.697)及恢复值(r=0.552)、术后9个月GFR(r=0.589)及恢复值(r=0.488)均呈显著正相关,差异有统计学意义(P0.05)。结论解除上泌尿道梗阻后患者的肾功能得到不同程度的恢复,即使是极重度肾功能损伤者,多数均能挽回患肾。术前RCT能有助于判断围手术期的肾功能,尤其是术后肾功能恢复情况。
[Abstract]:Objective to investigate the relationship between renal cortical thickness (RCT) and glomerular filtration rate (GFR) before and after unilateral upper urinary tract obstruction was relieved. Methods from July 2015 to June 2016, 63 patients with upper urinary tract obstruction were selected. Among them, there were 34 males and 29 females, aged 22 鈮,
本文编号:2529148
[Abstract]:Objective to investigate the relationship between renal cortical thickness (RCT) and glomerular filtration rate (GFR) before and after unilateral upper urinary tract obstruction was relieved. Methods from July 2015 to June 2016, 63 patients with upper urinary tract obstruction were selected. Among them, there were 34 males and 29 females, aged 22 鈮,
本文编号:2529148
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