代谢综合征对颈动脉内中膜厚度影响的性别差异研究
发布时间:2018-01-12 06:06
本文关键词:代谢综合征对颈动脉内中膜厚度影响的性别差异研究 出处:《中国全科医学》2016年20期 论文类型:期刊论文
【摘要】:目的探讨代谢综合征(MS)对颈动脉内中膜厚度(CIMT)影响的性别差异。方法选取2013-10-08至2014-02-25于皖北煤电集团总医院参加体检人群593例。受试者禁食8~12 h后,进行常规体检和生化指标检测;由经过培训的两名专业医师在短轴切面测量CIMT,取平均值。结果男性MS患病率为29.8%(105/353),女性MS患病率为24.6%(59/240),差异无统计学意义(χ~2=1.087,P0.05)。男性、绝经前后女性中,不同MS组分数者CIMT比较,差异均有统计学意义(F=12.240、8.850、9.510,P0.001)。男性、绝经前后女性0、1项组分者CIMT比较,差异有统计学意义(F=8.890、8.620,P0.001),其中,男性、绝经后女性0、1项组分者CIMT大于绝经前女性,差异有统计学意义(P0.05)。男性、绝经前后女性≥3项组分者CIMT比较,差异有统计学意义(F=0.670,P=0.002),其中,男性、绝经后女性≥3项组分者CIMT大于绝经前女性,绝经后女性CIMT大于男性,差异有统计学意义(P0.05)。Logistic回归分析显示,MS是女性CIMT增厚的危险因素〔OR=5.611,95%CI(1.398,22.632),P0.05〕,而未发现与男性CIMT增厚有关〔OR=1.091,95%CI(0.906,1.314),P0.05〕。结论 MS对CIMT的影响存在性别差异,MS对女性CIMT的影响更显著。
[Abstract]:Objective to investigate the effect of metabolic syndrome (MS) on carotid intima-media thickness (IMT). Methods from 2013-10-08 to 2014-02-25, 593 subjects were enrolled in the physical examination in the General Hospital of North Anhui Coal and Power Group. The subjects were fasting for 812 hours. Routine physical examination and biochemical index test; CIMT was measured on the short axis section by two trained physicians. Results the prevalence of MS in men was 29.88 / 105 / 353). The prevalence rate of MS in female was 24.60.59 / 240%, and there was no significant difference (蠂 ~ (2 / 2) 1.087 / P 0.05) among male, premenopausal and postmenopausal women. The difference of CIMT in different MS groups was statistically significant (P < 0.05). There were significant differences in CIMT between male and postmenopausal women (P 0.001), and there were significant differences between male and postmenopausal women (P < 0.01). There was a significant difference in CIMT between one component (8.890) and 8.620 (P0.001). Among them, male, postmenopausal female were 0. The CIMT of one component was higher than that of premenopausal women, and the difference was statistically significant (P 0.05). The CIMT of male and female before and after menopause 鈮,
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