老年2型糖尿病患者睡眠质量与自主神经病变的相关性

发布时间：2018-02-01 10:02

本文关键词： 型糖尿病睡眠质量糖尿病神经病变　出处：《中国老年学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的分析老年2型糖尿病(T2DM)患者的睡眠质量与其自主神经病变的相关性。方法将94例老年T2DM患者,按匹兹堡睡眠质量指数(PSQI)分为睡眠良好组(36例)和睡眠障碍组(58例)。测定并比较两组的生化指标、心率变异性(HRV)及血儿茶酚胺水平变化,并对睡眠质量影响因素行Logistic回归分析。结果经降糖用药后,良好组患者的体重指数(BMI)、空腹血糖(FPG)、糖化血红蛋白(Hb A1c)、空腹胰岛素(FINS)水平均明显低于障碍组(P0.05)。障碍组的病程明显长于良好组(P0.05),且HRV指标、儿茶酚胺水平明显低于良好组(均P0.05)。Logistic回归分析发现,睡眠障碍与病程、BMI、FINS呈正相关,与FPG呈负相关。结论老年T2DM患者睡眠质量可能与自主神经病变存在相关性,是糖尿病自主神经病变的表现之一。
[Abstract]:Objective to analyze the correlation between sleep quality and autonomic neuropathy in elderly patients with type 2 diabetes mellitus (T2DM). According to Pittsburgh Sleep quality Index (PSQI), 36 cases were divided into good sleep group (36 cases) and sleep disorder group (58 cases). The biochemical indexes of the two groups were measured and compared. The changes of heart rate variability (HRV) and serum catecholamine levels were analyzed by Logistic regression analysis. Results after hypoglycemic therapy, the body mass index (BMI) of the patients in the good group was higher than that in the control group. Fasting blood glucose (FPGN), glycosylated hemoglobin (HbA1c). Fasting insulin (fins) level was significantly lower than that in the disorder group (P 0.05A). The course of disease in the disorder group was significantly longer than that in the good group (P 0.05), and the HRV index. The level of catecholamine was significantly lower than that in the good group (P 0.05). Logistic regression analysis showed that sleep disorder was positively correlated with BMI-fins. Conclusion the sleep quality of elderly patients with T2DM may be correlated with autonomic neuropathy, which is one of the manifestations of diabetic autonomic neuropathy.
【作者单位】：内蒙古民族大学附属医院内分泌科;
【分类号】：R587.2
【正文快照】： 睡眠状况与健康的关系已引起广泛关注。2型糖尿病(T2DM)患者或多或少地存在着不同程度的睡眠质量下降的现象。研究显示[1],T2DM患者中睡眠质量不佳高达77%,远高于非T2DM患者。睡眠质量问题对老年T2DM患者的血糖具有一定的控制作用[2]。另外,睡眠紊乱可引起或加重精神状态和情

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