北京45～50岁居民碘营养状况与甲状腺结节关系

发布时间：2018-02-24 21:41

本文关键词： 碘营养尿碘甲状腺结节危险因素　出处：《中国公共卫生》2017年05期 　论文类型：期刊论文

【摘要】：目的调查分析45~50岁北京市居民甲状腺结节患病与碘营养状况的相关性。方法于2014年在北京市4个区的体检中心随机抽样方法选取1 041名45~50岁正常体检人群,问卷调查人口学信息及甲状腺结节发病可能的危险因素,收集晨尿测定尿碘含量,B超诊断甲状腺结节情况。结果共收集调查对象1 041人,总人群尿碘为1.3~2 660.4μg/L,中位数为143.3μg/L,男性尿碘中位数(154.2μg/L)高于女性(127.3μg/L),郊区(158.8μg/L)高于城区(113.8μg/L),差异均有统计学意义(均P0.05);B超共检出有甲状腺结节者366人(甲状腺结节组),占35.2%,女性检出率(43.9%)高于男性(28.2%);甲状腺结节组尿碘中位数为134.9μg/L,对照组尿碘中位数为145.8μg/L,2者差异无统计学意义;logistic回归分析结果显示,女性(OR=1.903)和遗传因素(OR=2.300)为患有甲状腺结节的危险因素。结论北京市45~50岁居民碘营养水平处于适宜范围,而甲状腺结节患病率较高,甲状腺结节的高发与碘摄入量的不足或过量无统计学意义,其危险因素仍需进一步研究。
[Abstract]:Objective to investigate and analyze the correlation between thyroid nodule disease and iodine nutritional status in Beijing residents aged 45 to 50 years. Methods in 2014, 1 041 healthy subjects aged 45 to 50 years were randomly selected from the physical examination centers in four districts of Beijing. A questionnaire survey was conducted on demographic information and possible risk factors for thyroid nodule. Morning urine was collected to determine urinary iodine content and B-mode ultrasound was used to diagnose thyroid nodule. The urinary iodine of the total population was 1.32660.4 渭 g / L, the median was 143.3 渭 g / L, the median of urinary iodine in men was 154.2 渭 g / L, which was higher than that in women (127.3 渭 g / L), and in the suburbs 158.8 渭 g / L was higher than that in urban areas (113.8 渭 g / L), the difference was statistically significant (all P0.05; B ultrasound detected 366 cases with thyroid nodules (thyroid nodules, 35.2um, female). The median urinary iodine was 134.9 渭 g / L in thyroid nodule group and 145.8 渭 g / L in control group. Conclusion the iodine nutrition level of the residents aged 45 to 50 years old in Beijing is in the appropriate range, and the prevalence of thyroid nodules is higher. The high incidence of thyroid nodules has no statistical significance with insufficient or excessive iodine intake, and its risk factors need further study.
【作者单位】：北京市疾病预防控制中心传染病地方病控制所;北京市体检中心;
【分类号】：R581

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