毓麟珠治疗脾肾阳虚型卵巢早衰的临床观察

发布时间：2018-02-27 14:52

本文关键词： 毓麟珠卵巢早衰脾肾阳虚临床观察　出处：《中华中医药学刊》2016年10期 　论文类型：期刊论文

【摘要】：目的:观察毓麟珠治疗脾肾阳虚型卵巢早衰(POF)的临床疗效。方法:将56例卵巢早衰患者随机分成两组,治疗组28例,采用中药毓麟珠加西药克龄蒙治疗;对照组26例,只采用西药克龄蒙,3个月为1个疗程,两组均连续治疗2个疗程后停药观察1个疗程。主要观察两组的低刺激素症状改善情况及激素水平变化。结果:两组治疗后临床低雌激素证候群改善情况比较,治疗组优于对照组,两组比较有显著性差异(P0.05);两组患者治疗后促卵泡生成素(FSH)和血清雌二醇(E2)与治疗前比较,均有极显著性差异(P0.01),治疗后两组血清黄体生成素(LH)水平均明显下降,与治疗前比较,均有显著性差异(P0.05);停药时治疗组和对照组总有效率分别为92.86%和88.46%,两组比较,有显著性差异(P0105);停药后3个月治疗组和对照组总有效率分别为92.86%和76.92%,两组比较,有显著性差异(P0.05)。结论:毓麟珠配合激素治疗可以改善脾肾阳虚型卵巢早衰患者症状,改善卵巢功能作用持久,疗效稳定,具有较强优势。
[Abstract]:Objective: to observe the clinical effect of Yulin Zhu in the treatment of premature ovarian failure with deficiency of spleen and kidney yang. Methods: 56 cases of premature ovarian failure were randomly divided into two groups: treatment group (n = 28) treated with traditional Chinese medicine Yulin Zhu and western medicine Ke Ling Meng, and control group (n = 26). Only take western medicine Ke Ling Meng, 3 months as a course of treatment, After two consecutive courses of treatment, the two groups were stopped to observe one course of treatment. The improvement of hypostimulin symptoms and hormone levels in the two groups were mainly observed. Results: the improvement of clinical low estrogen syndrome group was compared between the two groups after treatment. The treatment group was superior to the control group, the difference between the two groups was significant (P 0.05), the FSHs of follicle stimulating hormone (FSH) and serum estradiol E _ 2 (E _ 2) in the two groups were compared with those before treatment. The levels of serum luteinizing hormone (LH) in the two groups were significantly decreased after treatment, compared with those before treatment, the total effective rates of the treatment group and the control group were 92.86% and 88.46, respectively. The total effective rates of treatment group and control group were 92.86% and 76.92, respectively. Conclusion: Yulin Zhu combined with hormone therapy can improve the symptoms of premature ovarian failure with deficiency of spleen and kidney yang. The effect of improving ovarian function is lasting, the curative effect is stable, and has strong superiority.
【作者单位】：首都医科大学中医药学院;首都医科大学附属北京妇产医院;
【基金】：国家自然科学基金面上项目(81073096) 北京中医药薪火传承“3+3”工程项目(2012-SZ-C-41) 北京市中医药科技专项项目(JJ-200301) 首都医科大学中医药专项项目(15ZY05)
【分类号】：R711.75

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