皮肤型结节性多动脉炎并发周围神经炎

发布时间：2018-03-03 20:13

本文选题：皮肤型结节性多动脉炎　切入点：白色萎缩　出处：《临床皮肤科杂志》2017年06期 　论文类型：期刊论文

【摘要】：报告1例皮肤型结节性多动脉炎并发周围神经炎。患者女,40岁。双下肢斑疹、紫癜、结痂伴麻木疼痛5年,加重5个月。皮肤科检查:双小腿、足背散在褐黄色胡椒粉样色素沉着,部分呈环状分布。双踝内、外侧有可触及的紫癜、点状坏死、结痂、象牙白色萎缩性瘢痕。皮损组织病理:真皮浅层小血管栓塞,真皮深层中等大小动脉周围淋巴细胞和组织细胞浸润,伴管腔纤维蛋白样坏死。左侧腓肠神经组织病理:重度轴索性周围神经改变。该患者诊断为皮肤型结节性多动脉炎并发周围神经炎。给予泼尼松和羟氯喹抗炎,西洛他唑和胰激肽原酶肠溶片等抗血小板聚集、扩血管,甲钴胺和呋喃硫胺营养神经治疗后,皮损基本痊愈,神经症状部分缓解。随访1年无复发。
[Abstract]:A case of cutaneous nodular polyarteritis complicated with peripheral neuritis was reported. The patient was 40 years old. The dorsal foot is scattered in brown-yellow pepper-like pigmentation, some of which are circularly distributed. There are palpable purpura, punctate necrosis, scab, ivory white atrophic scar in the inside and outside of the ankle. Histopathology: small vascular embolism in the superficial dermis. The infiltration of lymphocytes and histocytes around the middle and large arteries in the deep dermis. Left sural nerve histopathology: severe axonal peripheral nerve changes. This patient was diagnosed as cutaneous nodular polyarteritis complicated with peripheral neuritis. Prednisone and hydroxychloroquine were given to prevent inflammation. Cilostazol and pancreatic kallikrein enteric-coated tablets inhibited platelet aggregation, vasodilation, methylcobalamin and furanthiamine nutritional neurotherapy, the lesions were basically cured, and the neurological symptoms were partly relieved. No recurrence was observed for one year.
【作者单位】：上海交通大学医学院附属瑞金医院皮肤科;上海交通大学医学院附属瑞金医院神经内科;
【分类号】：R593.27;R745

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