激素补充治疗用于围绝经期综合征的成本分析研究

发布时间：2018-03-10 01:39

本文选题：激素补充治疗　切入点：围绝经期综合征　出处：《中国卫生经济》2017年01期 　论文类型：期刊论文

【摘要】：目的:通过比较激素补充治疗(HRT)和中药治疗围绝经期综合征的成本,评估HRT的经济学效益。方法:本研究基于丹麦骨质疏松预防研究(DOPS)模型,以10万名围绝经期妇女为队列,采用成本效果分析法分析一年期和五年期直接治疗成本和间接治疗成本。结果:在疗效同等的假设下,对比中药治疗组HRT组一年期可减少骨折发生例数60例,减少心血管事件发生数188例,五年期减少骨折发生例数298例,减少心血管事件发生数923例;按65%依从性计算,HRT组相比中药治疗组一年期6 631.14万元,可以节约总治疗成本7 295.21万元;五年期可以降低药费28 541.48万元,可以节约总治疗成本31 372.70万元。结论:HRT治疗相比于中药治疗产生的费用更低,且具有良好的远期获益,可以节约卫生资源,减轻患者负担,是治疗围绝经期综合征的较好治疗方案。
[Abstract]:Objective: to compare the cost of hormone replacement therapy (HRT) and traditional Chinese medicine (TCM) in the treatment of peri-menopausal syndrome and to evaluate the economic benefits of HRT. Methods: the study was based on the Danish osteoporosis prevention study (DOPS) model and was cohort of 100,000 peri-menopausal women. Cost effect analysis was used to analyze the cost of direct treatment and indirect treatment for one year and five years. Results: under the assumption of the same curative effect, 60 cases of fracture were reduced in the HRT group compared with the traditional Chinese medicine group. The incidence of cardiovascular events was reduced in 188 cases, the number of fractures in five years was reduced in 298 cases, and the incidence of cardiovascular events was reduced in 923 cases. The total treatment cost can be saved by seventy-two million nine hundred and fifty-two thousand and one hundred yuan, the drug cost by two hundred and eighty-five million four hundred and fourteen thousand and eight hundred yuan in five years, and the total treatment cost by three hundred and thirteen million seven hundred and twenty-seven thousand yuan. Conclusion compared with traditional Chinese medicine treatment, the cost of the treatment is lower than that of traditional Chinese medicine, and it has good long-term benefits. It can save health resources and lighten the burden of patients. It is a better treatment for perimenopausal syndrome.
【作者单位】：上海市卫生发展研究中心;复旦大学公共卫生学院;格罗宁根大学;
【分类号】：R711.75

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