结缔组织病相关性肺间质病变的高分辨CT表现
本文选题:结缔组织病 切入点:肺间质病变 出处:《中南大学学报(医学版)》2017年08期 论文类型:期刊论文
【摘要】:目的:分析结缔组织病相关性肺间质病变(connective tissue associated interstitial lung disease,CTD-ILD)的高分辨CT(high resolution computed tomography,HRCT)表现。方法:收集中南大学湘雅医院2013年9月至2015年9月结缔组织病患者127例,所有患者均经临床实验室检查或病理学检查确诊为结缔组织病,且HRCT证实存在肺间质病变,回顾性分析患者的肺部HRCT影像表现。结果:127例患者结缔组织病分类包括类风湿关节炎36例(28.3%),皮肌炎及多肌炎34例(26.8%),系统性硬化症31例(24.4%),干燥综合征18例(14.2%),混合性结缔组织病7例(5.5%),系统性红斑狼疮1例(0.8%)。根据HRCT表现分为非特异性间质性肺炎(nonspecific interstitial pneumonia,NSIP)77例(60.6%),寻常型间质性肺炎(usual interstitial pneumonia,UIP)46例(36.2%),淋巴细胞性间质性肺炎(lymphocytic interstitial pneumonia,LIP)2例(1.6%),隐源性机化性肺炎(cryptogenic organizing pneumonia,COP)1例(0.8%),急性间质性肺炎(acute interstitial pneumonia,AIP)1例(0.8%)。36例类风湿关节炎相关性肺间质病变的HRCT表现为UIP(24例,66.7%)和NSIP(12例,33.3%)。34例皮肌炎及多肌炎相关性肺间质病变的HRCT表现为NSIP(32例,94.1%),UIP和COP(各1例,各占2.9%)。31例系统性硬化症相关性肺间质病变的HRCT表现为NSIP(21例,67.8%)和UIP(9例,29.0%),LIP(1例,3.2%)。18例干燥综合征相关性肺间质病变的HRCT表现为NSIP(9例,50.0%),UIP(8例,44.4%)和LIP(1例,5.6%)。7例混合型CTDILD的HRCT表现为UIP(4例,57.1%)和NSIP(3例,42.9%)。系统性红斑狼疮仅见1例AIP。结论:不同类型CTD-ILD的HRCT表现具有相对独特的特点。
[Abstract]:Objective: to analyze the high resolution CT(high resolution computed tomography-HRCTs of connective tissue associated interstitial lung disease (CTD-ILD). Methods: from September 2013 to September 2015, 127 patients with connective tissue disease (CTD-ILD) in Xiangya Hospital of Central South University were collected. All the patients were diagnosed as connective tissue disease by clinical laboratory or pathological examination, and the pulmonary interstitial disease was confirmed by HRCT. Results the classification of connective tissue disease included 36 cases of rheumatoid arthritis, 36 cases of rheumatoid arthritis, 34 cases of dermatomyositis and polymyositis, 31 cases of systemic sclerosis, 18 cases of Sjogren's syndrome, and 14 cases of mixed disease. 7 cases of connective tissue disease and 1 case of systemic lupus erythematosus were divided into nonspecific interstitial pneumonia, nonspecific interstitial pneumoniae, 77 cases with nonspecific interstitial pneumoniae, 46 cases with normal interstitial pneumoniae, 46 cases with UIPA, 2 cases with lymphocytic interstitial pneumonia, 2 cases with lymphocytic interstitial pneumoniae and 2 cases with cryptogenic interstitial pneumonia. One case of Cryptogenic organizing pneumoniae with acute interstitial pneumonia, one case of acute interstitial pneumoniae with acute interstitial pneumonia, one case with acute interstitial pneumonia, one case with acute interstitial pneumoniae, 36 cases with rheumatoid arthritis associated with pulmonary interstitial disease (UIP(24 case: 66.7am) and NSIP(12 case case case (33.33.34 cases of dermatomyositis and polymyositis associated pulmonary interstitial disease), the HRCT manifestation of acute interstitial pneumonia and polymyositis associated with pulmonary interstitial disease were as follows: 1 case: 0. 8%; 1 case of acute interstitial pneumonia; 1 case of acute interstitial disease; One case of NSIP(32 (1 case each) was treated with UIP and (1 case) with COP (1 case each). The HRCT manifestations of 31 cases of pulmonary interstitial disease associated with systemic sclerosis are NSIP(21 (67.8) and UIP(9 29.00.The HRCT manifestations of 18 cases of Sjogren syndrome associated pulmonary interstitial disease are NSIP(9 (50.0%) and LIP(1 (5.6%) and LIP(1 (5.6%). The HRCT manifestations of mixed CTDILD are as follows: 1 case of Sjogren's syndrome associated pulmonary interstitial disease (NSIP(9 case: 50. 0%) and 5. 6% of LIP(1 case of mixed CTDILD. UIP(4 (57.1%) and NSIP(3 (42.9%). Only one case of systemic lupus erythematosus was found. Conclusion: the HRCT features of different types of CTD-ILD are relatively unique.
【作者单位】: 中南大学湘雅医院放射科;
【基金】:国家自然科学基金(81500001)~~
【分类号】:R563;R593.2;R816.41
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