优化运动敏感驱动平衡预备的平衡稳态自由进动序列的应用

发布时间：2018-03-18 18:08

本文选题：糖尿病　切入点：iMSDE　出处：《实用医学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的:评价基于非对比增强磁共振血管成像(NCE-MRA)技术的优化运动敏感驱动平衡(iMSDE)预备的平衡稳态自由进动(bSSFP)序列在糖尿病患者下肢血管成像中的应用价值。方法:这项前瞻性研究招募了35例Ⅱ型糖尿病患者并在1.5TMR扫描仪上先后进行NCE-MRA和CE-MRA检查;获得的MIP图像由两位放射学医师进行双盲评分并以CE-MRA为参考标准检测NCE-MRA对血管狭窄的诊断精度;两者间血管诊断价值血管段比率的比较采用χ~2检验。结果:NCE-MRA在盆腔段血管中诊断价值血管段比率较CE-MRA降低。两位医师对NCE-MRA组图像的敏感性、特异性、阳性预测值、阴性预测值以及NCE-MRA准确率分别为95%/87%、96%/95%、57%/72%、99%/99%、96%/95%(κ=0.76)。结论:此项基于NCE-MRA技术的iMSDE预备的bSSFP序列可有效的显示糖尿病患者下肢动脉病变,并且具备不使用造影剂、扫描时间短优点以及大腿及小腿段血管具备较好的诊断价值。
[Abstract]:Objective: to evaluate the application value of balanced steady-state free precession (bSSFPFP) sequence prepared by non-contrast enhanced magnetic resonance angiography (NCE-MRA) technique in patients with diabetes mellitus (DM). Methods:. The prospective study recruited 35 patients with type 2 diabetes and performed NCE-MRA and CE-MRA examinations on a 1.5T Mr scanner. The obtained MIP images were scored by two radiologists and the accuracy of NCE-MRA in the diagnosis of vascular stenosis was detected by using CE-MRA as the reference standard. 蠂 ~ 2 test was used to compare the ratio of diagnostic value of vascular segment between the two groups. Results the ratio of diagnostic value of vascular segment in the pelvic segment was lower than that of CE-MRA. The sensitivity, specificity and positive predictive value of the two physicians to the images of the NCE-MRA group were higher than those of the control group. The negative predictive value and the accuracy of NCE-MRA were 95 / 87 and 96 / 95, respectively. They were 57 / 72, and 99 / 99 / 99, 96 / 95, respectively. Conclusion: the bSSFP sequence prepared by iMSDE based on NCE-MRA technology can effectively display arterial lesions in the lower extremities of diabetic patients, and it has no contrast agent. The advantages of short scanning time and the blood vessels of thigh and leg have good diagnostic value.
【作者单位】：南方医科大学非直属附属广东省第二人民医院影像中心;新疆维吾尔自治区人民医院影像中心;
【基金】：广东省第二人民医院青年基金项目(编号:YQ2015-015)
【分类号】：R445.2;R587.2

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