胃转流术对胃癌合并2型糖尿病患者血糖影响的临床研究

发布时间：2018-03-22 00:22

本文选题：Roux-en-Y消化道重建术　切入点：胃癌　出处：《中外医疗》2015年12期 　论文类型：期刊论文

【摘要】：目的探讨Roux-en-Y消化道重建术对胃癌合并2型糖尿病患者血糖的影响。方法回顾性分析该院于2010年—2014年6月收治的52例以Roux-en-Y消化道重建行手术治疗的胃癌合并2型糖尿病患者,比较术前、术后1、3、6个月的空腹血糖、餐后2 h血糖、糖化血红蛋白(HbA1c)、体重指数(BMI)的变化情况,密切关注术后的降糖药物使用情况。结果Roux-en-Y消化道重建术术后所有患者的空腹及餐后血糖均较术前逐渐降低(P0.05),伴随着术后血糖的改善,HbA 1c较术前逐渐下降(P0.05);患者术后各时间段BMI较术前均无明显变化(PO.05)。52例患者中,8例(15.3%)术后出院时血糖达正常水平,停用降糖药物;17例(32.7%)于术后3个月内停药;9例(17.3%)于术后3~6个月停药;18例(34.6%)于术后6个月仍在使用降糖药物,但用药剂量均有不通程度的减少,目前仍在随访。结论 Roux-en-Y消化道重建术是治疗2型糖尿病的有较方法。
[Abstract]:Objective to investigate the effect of Roux-en-Y alimentary tract reconstruction on blood glucose in patients with gastric cancer complicated with type 2 diabetes mellitus. Methods 52 cases of gastric cancer complicated with type 2 diabetes mellitus treated with Roux-en-Y gastrointestinal reconstruction from 2010 to June 2014 were retrospectively analyzed. The changes of fasting blood glucose (FBG), postprandial blood glucose (2 h), glycosylated hemoglobin (HbA1cU), and body mass index (BMIs) were compared before and after 1, 3 and 6 months postoperatively. Results the fasting and postprandial blood glucose of all patients after Roux-en-Y alimentary tract reconstruction was decreased gradually compared with that before operation (P 0.05), and with the improvement of blood glucose after operation, HbA1c decreased gradually compared with that before operation (P 0.05). There was no significant change in BMI at each time after operation compared with that before operation. Among 52 patients with PO.050.52 cases, 8 cases (15.3%) blood glucose reached normal level when discharged from hospital after operation. (17 cases stopped using hypoglycemic drugs 32.7%) within 3 months after operation, 9 cases (17.3%) and 18 cases (34.6 cases) were still using hypoglycemic drugs at 6 months after operation, but the dosage of these drugs were all decreased to a certain extent. Conclusion Roux-en-Y alimentary tract reconstruction is a better method for the treatment of type 2 diabetes mellitus.
【作者单位】：石河子大学医学院第一附属医院胃肠甲状腺外科;
【分类号】：R735.2

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