老年艾滋病住院患者的临床特点

发布时间：2018-03-26 06:41

本文选题：老年人　切入点：艾滋病　出处：《中国艾滋病性病》2017年05期

【摘要】：目的分析老年艾滋病(AIDS)住院患者的临床特点。方法收集中南医院2014年8月至2016年8月收治的756例AIDS住院患者的临床资料,按年龄是否超过60岁分为老年组患者(75例)与非老年组患者(681例)。采用病例对照研究,分析老年AIDS住院患者的临床特征,应用SPSS 20.0软件进行统计分析。结果老年组75例AIDS住院患者中,男性占63例(84.00%);平均年龄(65.55±5.27)岁;主要经性传播感染(59例,78.67%);平均CD4+T淋巴细胞计数为(137.45±153.63)个/μL;进行抗反转录病毒治疗39例(52.00%)。老年组住院期间病死率(6.67%)高于非老年组(1.47%),差异有统计学意义(P=0.009)。老年组主要因机会性感染住院(65例,86.67%),其中细菌性肺炎(χ2=4.863,P=0.027)、隐球菌脑膜炎(χ2=5.325,P=0.021)的患病率高于非老年组。此外,老年组的药物性肾损害的发生率也高于非老年组(χ2=5.766,P=0.016)。结论老年AIDS住院患者以性传播为主,男性多见,住院原因主要为机会性感染,细菌性肺炎及新隐球菌脑膜炎患病率高于年轻人,药物性肾损害发生率高,住院期间病死率高于年轻人。
[Abstract]:Objective to analyze the clinical characteristics of AIDS (AIDS) in elderly hospitalized patients. Methods from August 2014 to August 2016 Zhongnan Hospital treated 756 cases of AIDS hospitalized patients with clinical data, according to the age is over 60 years old were divided into elderly patients (75 cases) and non elderly group (681 cases). A case-control study of elderly AIDS hospitalized patients with clinical features, SPSS 20 software was used for statistical analysis. Results 75 cases of the elderly group AIDS patients, men accounted for 63 cases (84%); the average age (65.55 + 5.27) years; mainly by sexually transmitted infections (59 cases, 78.67%); the average CD4+T lymphocyte count is (137.45 + 153.63) a L / mu; antiretroviral therapy in 39 cases (52%). The mortality of elderly group (6.67%) was higher than in non elderly group (1.47%), the difference was statistically significant (P=0.009). The elderly group mainly because the machine will of hospital infection (65 cases, 86.67%), the bacterial Pneumonia (2=4.863, P=0.027), cryptococcal meningitis (2=5.325, P=0.021) prevalence rate is higher than the non elderly group. In addition, the incidence of drug-induced renal damage in elderly group was higher than that in the non elderly group (2=5.766, P=0.016). Conclusion the hospitalized elderly AIDS patients were mainly sexually transmitted, male, hospitalization the main reason for opportunistic infections, bacterial pneumonia and cryptococcal meningitis prevalence was higher than young people, drug-induced renal injury rate is high, the case fatality rate is higher than that of young people.

【作者单位】：武汉大学中南医院感染科;
【分类号】：R512.91

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