糖尿病对经皮冠状动脉介入治疗患者长期预后的影响

发布时间：2018-03-31 20:02

本文选题：冠心病　切入点：糖尿病　出处：《中国动脉硬化杂志》2016年07期

【摘要】：目的探讨糖尿病对经皮冠状动脉介入治疗(PCI)患者长期预后的影响。方法连续入选2367例接受PCI的冠心病患者,根据有无糖尿病分为两组:糖尿病组(719例)及非糖尿病组(1648例),通过COX回归分析研究糖尿病对PCI患者长期预后的影响。结果与非糖尿病组相比,糖尿病组男性更少,甘油三酯、N端B型利钠肽原更高,高密度脂蛋白胆固醇更低,合并陈旧性心肌梗死、心功能不全、高血压、肾功能不全、脑卒中的比例更高。糖尿病组患者冠状动脉3支病变比例、慢性闭塞比例、Gensini评分更高,平均支架个数更多,平均支架长度更长。术后随访显示,两组患者的全因死亡、主要不良心血管事件、心源性死亡、非致死性心肌梗死、非计划再次血运重建均无显著差异。多因素COX回归分析显示,糖尿病与PCI患者长期预后无显著相关。结论合并糖尿病的PCI患者在临床方面存在特殊性,但长期预后并无显著不良。
[Abstract]:Objective to investigate the effect of diabetes mellitus on the long-term prognosis of patients undergoing percutaneous coronary intervention (PCI). Methods 2367 consecutive patients with PCI were enrolled in this study. Patients with diabetes were divided into two groups: diabetic group (n = 719) and non-diabetic group (n = 1648). The effect of diabetes on long-term prognosis of patients with PCI was studied by COX regression analysis. The N-terminal B-type natriuretic peptide of triglyceride was higher, the high density lipoprotein cholesterol was lower, the patients with old myocardial infarction, heart failure, hypertension, renal insufficiency, The ratio of coronary artery disease to chronic occlusion was higher, the mean number of stents was higher, and the mean stent length was longer. There were no significant differences in major adverse cardiovascular events, cardiogenic death, non-fatal myocardial infarction and unplanned re-revascularization. Multivariate COX regression analysis showed that. Conclusion the long-term prognosis of PCI patients with diabetes mellitus is not significantly bad, but there is no significant correlation between the long-term prognosis of PCI patients with diabetes mellitus and the long-term prognosis of PCI patients.
【作者单位】：中国医科大学附属盛京医院心内科;
【基金】：辽宁省科技厅社会发展攻关计划(2011225020)
【分类号】：R587.1;R541.4

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