雌激素和骨标志物与绝经后妇女骨质疏松的关系

发布时间：2018-04-04 02:25

  本文选题：雌激素　切入点：骨标志物　出处：《中国老年学杂志》2017年02期

【摘要】：目的探讨雌激素和骨标志物与绝经后妇女骨质疏松(OP)的关系。方法绝经后OP妇女71例为观察组,同期绝经后无OP妇女71例为对照组,行雌激素和骨标志物检测并分析其与绝经后妇女OP的相关性。结果观察组雌二醇、孕酮、骨密度值低于对照组(P0.05)。观察组促卵泡成熟激素、促黄体生成激素、β-胶原降解产物、总骨Ⅰ型前胶原氨基酸延长链、骨钙素N端中分子高于对照组(P0.05)。雌二醇、孕酮、骨密度值与OP呈明显负相关。促卵泡成熟激素、促黄体生成激素、β-胶原降解产物、总骨Ⅰ型前胶原氨基酸延长链、骨钙素N端中分子与OP呈明显正相关。结论雌激素和骨标志物与绝经后妇女OP的关系密切。监测雌激素和骨标志物可及早发现骨代谢异常,有助于防治绝经后妇女OP。
[Abstract]:Objective to investigate the relationship between estrogen and bone markers and osteoporosis (OPN) in postmenopausal women.Methods 71 postmenopausal op women as observation group and 71 postmenopausal non-op women as control group. Estrogen and bone markers were detected and their correlation with op in postmenopausal women was analyzed.Results the values of estradiol, progesterone and bone mineral density in the observation group were lower than those in the control group (P 0.05).In the observation group, follicle maturation hormone, luteinizing hormone, 尾 -collagen degradation product, amino acid chain of total procollagen 鈪，

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