新疆乌鲁木齐市某社区维吾尔族女性跟骨骨密度与代谢综合征相关性分析

发布时间：2018-04-08 07:37

本文选题：维吾尔族　切入点：绝经后女性　出处：《中国骨质疏松杂志》2017年05期

【摘要】：目的探索代谢综合征(MS)与不同年龄及代谢状态下维吾尔族女性定量骨超声检测跟骨骨密度(T值)与其之间的相关性。方法横断面研究,对象为新疆乌鲁木齐市二道桥某社区常住维族女性。按年龄分组,观察不同年龄段维族女性骨量的变化。按中华医学会糖尿病分会(CDS)[1]诊断MS的诊断标准,将549名女性分为高血压组136例,血压正常组413例;糖尿病组103例,血糖正常组446例;单纯肥胖或超重组290例,体重正常组259例;血脂紊乱组157例,血脂正常组392例;MS组86例,非MS组463例。根据既往史是否绝经分为未绝经组339例,绝经组182例;并用线性回归分析,研究跟骨骨密度的独立影响因素。结果高血压、糖代谢异常、MS组骨量T值均低于其代谢正常组,差异有统计学意义(均P0.05);高血压、糖代谢异常、超重或肥胖、MS组骨量减少、骨质疏松的患病率均高于其代谢正常组,差异有统计学意义(均P0.05);按年龄分组,不同组间T值不完全相同,随年龄增长,骨量减少的患病率升高,差异有统计学意义(P0.05);按是否合并绝经分组,绝经组骨量减少、骨质疏松的患病率明显升高,差异有统计学意义(P0.05)。结论 MS作为多种代谢异常的症候群,骨量减少的患病率高,是骨质疏松发生的高风险人群。绝经是女性骨量减少的独立危险因素。
[Abstract]:Objective to explore the correlation between metabolic syndrome (MSM) and Uygur women's calcaneal bone mineral density (BMD) measured by quantitative ultrasound under different ages and metabolic states.Methods Cross-sectional study was carried out among Uyghur women in Erdaoqiao, Urumqi, Xinjiang.The changes of bone mass of Uygur women in different age groups were observed.549 women were divided into hypertension group (136 cases), normal blood pressure group (413 cases), diabetes group (103 cases), normal blood glucose group (446 cases), simple obesity or hyperrecombination group (290 cases) and normal body weight group (259 cases).There were 157 cases in dyslipidemia group, 86 cases in MS group and 463 cases in non-MS group.According to the history of menopause, 339 cases were divided into unmenopausal group and 182 cases in menopausal group, and the independent influencing factors of calcaneal bone mineral density were studied by linear regression analysis.Results the T value of bone mass in MS group was lower than that in normal group (P 0.05), and the bone mass in MS group with hypertension, abnormal glucose metabolism, overweight or obesity was decreased.The prevalence rate of osteoporosis was higher than that of normal metabolism group (P 0.05).The difference was statistically significant (P 0.05), according to whether the menopause was combined with menopause, the bone mass of the menopausal group was decreased, and the prevalence rate of osteoporosis was significantly increased, and the difference was statistically significant (P 0.05).Conclusion MS, as a syndrome with multiple metabolic abnormalities, has a high prevalence of bone mass reduction and is a high risk group for osteoporosis.Menopause is an independent risk factor for reduced bone mass in women.
【作者单位】：新疆医科大学第一附属医院内分泌科;新疆乌鲁木齐米东区人民医院内科;新疆乌鲁木齐兵团医院内分泌科;
【基金】：新疆维吾尔自治区自然科学基金项目(2014211C058)
【分类号】：R589

【相似文献】