维生素D与2型糖尿病患者静力性平衡的相关性分析

发布时间：2018-04-24 08:05

  本文选题：维生素D + 型糖尿病　； 参考：《中国骨质疏松杂志》2016年12期

【摘要】：目的分析2型糖尿病患者不同维生素D水平组之间静力性平衡指标的差异,探讨维生素D对平衡功能的影响。方法对86名年龄32~78岁的2型糖尿病患者进行研究,测定体重指数、跟骨骨密度、25(OH)D3水平等指标,应用Foot Scan Balance7.7平板式足底压力测试系统评估静力性平衡功能,获得压力中心的移动轨迹总长度(TTW)及包绕95%压力中心移动轨迹在内的椭圆面积(EA)两项平衡参数,分析维生素D对平衡参数的影响。结果 86名受检者平均年龄(54.99±10.19)岁,男女比例40∶46,按照25(OH)D3水平分为3组:严重缺乏组(10 ng/ml,n=32);缺乏组(≥10 ng/ml而20 ng/ml,n=40);不足组(≥20 ng/ml而30 ng/ml,n=14)。维生素D严重缺乏组压力中心移动轨迹总长度(TTW)及包绕95%压力中心移动轨迹在内的椭圆面积(EA)明显高于不足组,差异存在统计学意义[(10.66±4.42)mm对(97.0±20.1)mm;(11.55±8.78)mm2对(6.58±2.68)mm2,P0.05]。多元逐步回归分析显示25(OH)D3水平与压力中心移动轨迹总长度(TTW)及包绕95%压力中心移动轨迹在内的椭圆面积(EA)成负相关,相关系数分别为-1.835和-0.247,P0.05。且独立于年龄、性别、跟骨骨密度等因素。结论糖尿病患者中维生素D水平同静力性平衡之间存在独立负相关,对糖尿病患者进行维生素D的筛查及补充仍有待进一步研究。
[Abstract]:Objective to study the effect of vitamin D on balance function in patients with type 2 diabetes mellitus. Methods 86 patients with type 2 diabetes mellitus aged 32 to 78 years were studied. Body mass index (BMI), calcaneal bone mineral density (BMD) and bone mineral density (BMD) of calcaneus were measured. The static balance function was evaluated by Foot Scan Balance7.7 plantar pressure test system. Two equilibrium parameters, TTW (total length of pressure center trajectory) and EAA (elliptical area), including the orbit around 95% pressure center, are obtained. The effects of vitamin D on the equilibrium parameters are analyzed. Results the average age of 86 subjects was 54.99 卤10.19 years old. The ratio of male and female was 40: 46. According to the level of 25(OH)D3, 86 subjects were divided into three groups: severe deficiency group (10 ng / ml), deficiency group (鈮，

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