以甘油三酯分层分析益糖康对并有糖调节受损痰热互结型代谢综合征的临床研究

发布时间：2018-04-27 07:08

  本文选题：代谢综合征 + 痰热互结　； 参考：《中华中医药学刊》2017年05期

【摘要】：目的:观察、评价中药复方益糖康从甘油三酯(TG)分层角度对并有糖调节受损(IGR)痰热互结型代谢综合征(MS)的临床研究。方法:选取2007年12月—2010年12月辽宁中医药大学、辽宁省中医药研究院、山东中医药大学附属医院、北京中医药大学东直门医院以及辽阳糖尿病专科医院5个中心收治的并痰热互结型MS患者165例,采用多中心、随机、双盲、安慰剂对照的设计原则,试验组予综合治疗并口服益糖康,对照组予综合治疗并口服安慰剂,疗程为12周,治疗前后分别检测两组2h PG、Hb A1c、TC、TG、BMI、收缩压、舒张压。结果:益糖康可降低患者2h PG、TC、TG、BMI、收缩压、舒张压,且疗效均优于对照组。以TG分层角度分析,当TG正常时,益糖康可降低患者的2h PG、BMI、收缩压、舒张压及LDL-C,当TG高时,益糖康可降低患者的BMI、收缩压、舒张压。结论:益糖康可改善并痰热互结型MS的治疗前患者2h PG、TC、TG、BMI、收缩压、舒张压,并对不同的TG分层有不同的作用。
[Abstract]:Objective: To observe and evaluate the clinical study of the Chinese medicine compound Yi Tang Kang (TG) from the triglyceride (TG) stratification angle and the impaired glucose regulation (IGR) phlegm interbed metabolic syndrome (MS). Methods: to select the Liaoning University of Traditional Chinese Medicine from December 2007 to December 2010, the hospital of traditional Chinese medicine in Liaoning, the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, and the east of Beijing University of Chinese Medicine. 165 cases of MS patients with phlegm heat intercourse were treated in 5 centers of direct gate hospital and Liaoyang diabetes specialist hospital. The design principle of multi center, random, double blindness and placebo control was adopted. The experimental group was treated with comprehensive treatment and Yiu Kang. The control group was treated with a comprehensive treatment and took a placebo for 12 weeks. Two groups of 2H PG, Hb A before and after treatment were detected respectively. 1C, TC, TG, BMI, systolic pressure, diastolic pressure. Results: Yi Tang Kang can reduce the patients 2H PG, TC, TG, BMI, systolic pressure, diastolic pressure, and the effect is better than the control group. When TG stratified angle analysis, when TG normal, the benefit sugar Kang can reduce the patient's 2h, systolic pressure, diastolic pressure, and decrease the patient's pressure, systolic pressure, diastolic pressure. Conclusion: Yi Tang Kang can improve the 2H PG, TC, TG, BMI, systolic blood pressure and diastolic blood pressure before treatment of MS with phlegm heat mutual type, and has different effects on different TG stratification.

【作者单位】： 辽宁中医药大学;
【基金】：国家“十二五”科技支撑计划项目(2014BAI10B04)
【分类号】：R589
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本文编号：1809712