CBP联合早期肠内营养治疗SAP合并高脂血症的效果分析

发布时间：2018-04-27 20:13

  本文选题：急性重症胰腺炎 + 高脂血症　； 参考：《重庆医学》2017年09期

【摘要】：目的观察连续性血液净化(CBP)联合早期肠内营养(EEN)治疗急性重症胰腺炎(SAP)合并高脂血症患者的效果。方法选择该院2014年1月至2015年10月收治的SAP合并高脂血症患者56例,按照随机数字表法分为CBP加EEN组(联合组)和CBP组各28例,CBP组采用CBP治疗,联合组在CBP组的基础上联合EEN(入院后2d内)治疗。治疗后观察两组患者临床疗效及各项指标改善情况。结果治疗后联合组总有效率(96.43%)高于CBP组(75.00%),两组比较差异有统计学意义(P0.05);两组治疗后三酰甘油(TG)、尿淀粉酶(UAMY)、血脂肪酶(LPS)、血淀粉酶(SAMY)、C反应蛋白(CRP)、乳酸脱氢酶(LDH)等相关指标均有下降,其中联合组较CBP组下降更明显(P0.05)。治疗后联合组急性生理学与慢性健康状况评分系统Ⅱ(APACHE-Ⅱ)评分明显低于CBP组(P0.05),联合组症状缓解时间及住院时间均短于CBP组(P0.05);联合组并发症发生率(10.71%)明显低于CBP组(28.57%),两组比较差异有统计学意义(P0.05)。结论 CBP联合早期EEN可明显改善SAP患者的预后,有效减低患者并发症。
[Abstract]:Objective to observe the effect of continuous blood purification (CBP) combined with early enteral nutrition (EEN) in the treatment of severe acute pancreatitis (SAP) with hyperlipidemia. Methods from January 2014 to October 2015, 56 SAP patients with hyperlipidemia were randomly divided into CBP plus EEN group (combined group) and CBP group (28 cases) treated with CBP. The combined group was treated with EEN (within 2 days after admission) on the basis of CBP. The clinical curative effect and the improvement of each index were observed after treatment. Results the total effective rate of the combined group (96.43) was higher than that of the CBP group (75.00%), and the difference between the two groups was statistically significant (P 0.05), and the related indexes such as triacylglycerol, urine amylase (UAMYN), lipase (LPSN), serum amylase SAMYC-reactive protein (CRPN) and lactate dehydrogenase (LDH) were all decreased after treatment. The decrease of P0. 05 in the combined group was more obvious than that in the CBP group. After treatment, the score of acute physiology and chronic health status scoring system 鈪，

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