类风湿血管炎的发病机制和治疗进展

发布时间：2018-04-29 11:44

本文选题：血管炎 + 类风湿关节炎　；参考：《河北医科大学》2017年硕士论文

【摘要】：类风湿关节炎(rheumatoid arthritis,RA)是一种以关节滑膜炎为主要表现的全身性自身免疫性疾病,除关节病变外还可有多种关节外病变。类风湿血管炎(rheumatoid vasculitis,RV)是RA最为严重的并发症之一,它主要累及中小血管,是一种破坏性、炎症性的病理过程,最终导致血管闭塞、组织或器官缺血坏死。其病因和发病机制尚未完全明确,本文将着重从自身抗体、免疫复合物与细胞因子、基因等方面介绍其发病机制以及治疗方面的有关研究进展。
[Abstract]:Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by synovitis. Rheumatoid vasculitis (RV) is one of the most serious complications of RA. It mainly involves small and medium blood vessels and is a destructive and inflammatory pathological process leading to vascular occlusion and ischemic necrosis of tissues or organs. Its etiology and pathogenesis have not been completely clear. This article will focus on the autoantibodies, immune complexes and cytokines, genes and other aspects of its pathogenesis and treatment of the related research progress.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R593.2

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