骨质疏松椎体压缩性骨折患者经皮椎体成形术中应用不同黏度骨水泥效果比较

发布时间：2018-04-30 07:42

本文选题：椎体压缩性骨折 + 骨质疏松　；参考：《山东医药》2016年32期

【摘要】：目的比较骨质疏松椎体压缩性骨折(OVCF)患者经皮椎体成形术(PVP)中应用不同黏度骨水泥的临床效果及安全性。方法选择OVCF患者70例,随机分为高黏度组和低黏度组各35例,分别采用高黏度和低黏度聚甲基丙烯酸甲酯骨水泥行PVP。比较两组单个椎体手术时间、骨水泥注入量,术前及术后1周疼痛视觉模拟评分(VAS)及Oswestry功能障碍指数(ODI),术后1周骨水泥分布情况、骨水泥渗漏情况及椎体再骨折发生率。结果两组单个椎体手术时间、骨水泥注入量比较差异均无统计学意义(P均0.05)。与术前比较,两组术后1周VAS及ODI均降低(P均0.01),两组术后比较差异均无统计学意义(P均0.05)。高黏度组骨水泥分布不均发生率、骨水泥渗漏发生率均低于低黏度组(P均0.05);两组术后椎体再骨折发生率比较差异无统计学意义(P0.05)。结论 PVP中应用高黏度或低黏度骨水泥治疗OVCF的效果均较好,但高黏度骨水泥的分布情况更好、安全性更高。
[Abstract]:Objective to compare the clinical efficacy and safety of different viscosity bone cement in percutaneous vertebroplasty (PVP) in patients with osteoporotic vertebral compression fracture (OVCF). Methods 70 patients with OVCF were randomly divided into high viscosity group (n = 35) and low viscosity group (n = 35). The time of single vertebra operation, the amount of bone cement injected, the visual analogue score of pain before operation and 1 week after operation, and the index of Oswestry dysfunction were compared between the two groups. The distribution of bone cement, the leakage of bone cement and the incidence of vertebral refracture 1 week after operation were compared between the two groups. Results there was no significant difference in the time of operation and the amount of bone cement injection between the two groups (P < 0.05). Compared with pre-operation, the VAS and ODI of the two groups decreased at 1 week after operation (P < 0.01), and there was no significant difference between the two groups (P < 0.05). The rate of bone cement leakage in the high viscosity group was lower than that in the low viscosity group (P < 0.05), and there was no significant difference between the two groups in the incidence of vertebral refracture. Conclusion the application of high viscosity or low viscosity bone cement in PVP is effective in the treatment of OVCF, but the distribution of high viscosity bone cement is better and the safety is higher.
【作者单位】：泰山医学院附属聊城市第二人民医院;
【基金】：卫生部医药卫生科技发展中心研究课题(W2014ZT156)
【分类号】：R687.3;R580

【相似文献】