山东省城市中老年人群血脂现状调查

发布时间：2018-05-04 03:25

  本文选题：山东省 + 中老年人　； 参考：《山东大学学报(医学版)》2017年05期

【摘要】：目的探讨不同糖代谢状态、性别、年龄、体质量指数(BMI)、血压与血脂水平的关系。方法对山东省40岁以上城市社区中老年人10 028名行横断面调查,收集人口学资料,同时行口服葡萄糖耐量试验,测定空腹总胆固醇(Cho)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和甘油三酯(TG)。结果山东省40岁以上城市社区中老年人血清Cho、LDL-C、HDL-C、TG平均水平分别为(5.35±1.05)mmol/L、(3.18±0.86)mmol/L、(1.51±0.38)mmol/L、1.34 mmol/L。女性血清Cho、LDL-C、HDL-C、TG平均水平均高于男性,其中Cho、LDL-C、HDL-C差异有统计学意义(P0.001)。血清Cho、LDL-C、TG平均水平随血压升高而升高(P=0.005,P=0.012,P=0.043),血清HDL-C平均水平随血压升高而降低(P=0.002)。血清Cho、LDL-C、TG平均水平随体质量指数增加而升高(P=0.013,P=0.023,P=0.007),血清HDL-C平均水平随体质量指数增加而降低(P=0.010)。糖耐量正常人群、糖尿病前期[空腹血糖受损(IFG)、糖耐量减低(IGT)及空腹血糖受损并糖耐量减低]人群、糖尿病人群血清Cho、LDL-C平均水平先升高后降低(P0.001),血清HDL-C平均水平逐渐降低(P=0.007),TG平均水平逐渐升高(P0.001)。血清Cho边缘升高(5.18~6.21 mmol/L)和升高(≥6.22 mmol/L)的人群分别为36.92%、19.10%;LDL-C边缘升高(3.37~4.13 mmol/L)和升高(≥4.14 mmol/L)人群分别为25.24%、13.39%;TG边缘升高(1.70~2.25 mmol/L)和升高(≥2.26 mmol/L)人群分别为16.70%、17.47%;HDL-C降低(≤1.04 mmol/L)的人群为5.64%。结论山东省城市中老年人群血清总胆固醇和低密度脂蛋白胆固醇水平升高。性别、年龄、BMI、血压、糖代谢状态均可影响血脂水平。如不采取有效的预防和控制措施,中国心脑血管疾病的发病率仍将持续升高。
[Abstract]:Objective to investigate the relationship between glycometabolism, sex, age, body mass index (BMI), blood pressure and blood lipid levels. Methods a cross-sectional study was conducted in 10028 middle aged and elderly people over 40 years old in Shandong Province, and the demographic data were collected and oral glucose tolerance test was performed to determine fasting total cholesterol (Cho) and low density lipoprotein cholesterol (L). DL-C), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG). Results the average level of serum Cho, LDL-C, HDL-C, TG in urban communities over 40 years old in Shandong province was (5.35 + 1.05) mmol/L, (3.18 + 0.86) mmol/L, (1.51 + 0.38) mmol/L, and 1.34 mmol/L. female serum Cho. The average level of serum Cho, LDL-C, TG increased with the increase of blood pressure (P=0.005, P=0.012, P=0.043), and the average level of serum HDL-C decreased with the increase of blood pressure (P=0.002). The average level of serum HDL-C increased with the increase of body mass index (P=0.002). The average level of serum HDL-C increased with body mass index (P=0.005, P=0.012, P=0.043). The average level of serum Cho increased with body mass index. The index increased and decreased (P=0.010). The people with normal glucose tolerance, pre diabetes [impaired fasting blood glucose (IFG), impaired glucose tolerance (IGT), impaired fasting blood glucose and impaired glucose tolerance], the serum Cho, LDL-C average level of diabetes population increased first and then decreased (P0.001), the serum HDL-C average level decreased gradually (P=0.007), and the average TG level gradually increased. High (P0.001). The population of serum Cho edge elevation (5.18~6.21 mmol/L) and elevation (> 6.22 mmol/L) were 36.92%, 19.10%; LDL-C marginal elevation (3.37~4.13 mmol/L) and elevated (4.14 mmol/L) population were 25.24%, 13.39%; TG margin increased (1.70~2.25 mmol/L) and increased (2.26 or 2.26) were 16.70%, 17.47%, respectively (less than 1). The population of.04 mmol/L) is the 5.64%. conclusion that the levels of serum total cholesterol and low density lipoprotein cholesterol in the middle and old people of Shandong province are increased. The sex, age, BMI, blood pressure, and glucose metabolism can affect the level of blood lipid. If no effective prevention and control measures are taken, the incidence of cardiovascular and cerebrovascular diseases in China will continue to rise.

【作者单位】： 山东大学齐鲁医院内分泌科;
【基金】：山东省重大专项资助项目(2014ZZCX02201)
【分类号】：R589.2
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本文编号：1841379