糖尿病患者唾液流率与口干相关性研究

发布时间：2018-05-04 21:14

  本文选题：糖尿病 + 口干　； 参考：《口腔医学研究》2016年02期

【摘要】：目的:调查糖尿病患者口干、唾液流率情况并研究其与代谢、病史的相关性。方法:入选1型、2型糖尿病患者21例和54例,同时选择年龄、性别相近的两组健康人群作为对照,在空腹状态下测定静止唾液流率,采用口干问卷(xerostomia questionnaire,XQ)评价4组人群的口干程度。结果:与对照组相比,两组糖尿病患者唾液流率均下降,但2型糖尿病下降程度较小(P0.05);两组糖尿病患者均诉一定程度的口干,OX量表得分高于对照组(P0.05);2型糖尿病患者唾液流率低于1型糖尿病,而OX评分高于1型糖尿病,但差异均无统计学意义(P0.05);以HbA1C≤6%和病史≤3年(2型糖尿病患者≤5年)为依据对糖尿病患者进行亚组分析,唾液流率和口干程度组间比较差异均无统计学意义(P0.05)。结论:糖尿病患者均有较明显的口干症状,同时唾液腺分泌均较正常人群减少,在糖尿病患者口腔保健工作中应引起重视。
[Abstract]:Objective: to investigate the relationship between dry mouth and salivary flow rate and metabolism and history of diabetes mellitus patients. Methods: 21 patients with type 1 diabetes mellitus and 54 patients with type 1 diabetes mellitus were enrolled in this study. Two groups of healthy people of similar age and sex were selected as control group. Xerostomia questionnaire (XQ) was used to evaluate the dryness of the four groups. Results: compared with the control group, the salivary flow rate decreased in both groups. However, the degree of decrease of type 2 diabetes mellitus was lower than that of type 2 diabetes mellitus (P 0.05), and the scores of OX scale in both groups were higher than those in the control group (P 0.05), but the saliva flow rate was lower than that in type 1 diabetes mellitus, while the OX score was higher than that in type 1 diabetes mellitus. However, there was no significant difference between the two groups (P < 0 05), and the subgroup analysis was based on HbA1C 鈮，

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