H型高血压对老年男性骨密度的影响

发布时间：2018-05-06 09:18

本文选题：H型高血压 + 高血压　；参考：《中国骨质疏松杂志》2016年07期

【摘要】：目的通过比较H型高血压、普通高血压和血压正常人群骨密度(Bone Mineral Density,BMD)情况,探讨H型高血压对BMD的影响。方法对绵阳地区城市、郊区及农村1215例70岁以上男性自愿者进行腰椎、股骨颈和股骨转子区BMD检测,符合标准纳入标准的有813人。骨密度按世界卫生组织(WHO)标准分类:骨量正常、骨量减少和骨质疏松。对参与者血压和血清同型半胱氨酸(Homocysteine,HCY)进行检测,根据中华医学HCY和血压的分类标准,高血压同时伴有血清HCY升高称为H型高血压。参与者血压情况分为三类:H型高血压患者、普通高血压患者及血压正常人群。比较三类人群BMD值、骨量减少和骨质疏松患病率。结果 H型高血压患者共有75例,普通高血压患者107例,正常人群631例。H型高血压患者BMD值显著低于普通高血压患者和血压正常人群,骨量减少和骨质疏松患病率显著高于普通高血压患者和血压正常人群(P0.05),普通高血压患者BMD值显著低于普通血压正常人群,骨量减少和骨质疏松患病率显著高于血压正常人群(P0.005)。结论老年男性中,高HCY和高血压对BMD的影响有交互作用,两者同时存在时BMD显著降低,骨量减少和骨质疏松显著升高。
[Abstract]:Objective to investigate the effect of H type hypertension on BMD by comparing the bone Mineral density (BMD) of patients with H type hypertension, normal blood pressure and normal blood pressure. Methods 1215 male volunteers over 70 years old in Mianyang city suburb and countryside were examined for BMD of lumbar vertebrae femoral neck and femoral trochanter. Bone mineral density (BMD) is classified according to the World Health Organization (WHO) standard: normal bone mass, osteopenia and osteoporosis. The blood pressure and serum homocysteine homocysteine (HCY) were measured. According to the classification standard of Chinese medical HCY and blood pressure, hypertension accompanied by elevated serum HCY was called H type hypertension. Participants' blood pressure was divided into three groups: type H hypertension, normal hypertension and normal blood pressure. The prevalence of BMD, osteopenia and osteoporosis were compared among the three groups. Results there were 75 cases of H type hypertension, 107 cases of normal hypertension and 631 cases of normal population. The BMD value of H type hypertension was significantly lower than that of normal hypertension and normal blood pressure. The prevalence rate of osteopenia and osteoporosis was significantly higher than that of normal hypertension and normal blood pressure (P 0.05), the BMD value of normal hypertension was significantly lower than that of normal blood pressure, and the prevalence of osteopenia and osteoporosis was significantly higher than that of normal blood pressure (P 0.005). Conclusion High HCY and hypertension have an interactive effect on BMD in elderly men. BMD decreased significantly, bone mass decreased and osteoporosis increased significantly in the presence of both.
【作者单位】：绵阳市第三人民医院老年综合科(骨质疏松专科);绵阳市第三人民医院妇科;
【基金】：四川省科技支撑计划(2010FZ0061);四川省科技支撑计划(2013FZ0051) 四川省杰出青年培养计划(2012JQ0050)
【分类号】：R580;R544.1

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