低钠血症治疗量在细胞外液与骨的再分布

发布时间：2018-05-08 00:46

本文选题：低钠血症 + 骨钠　；参考：《山西医科大学》2017年硕士论文

【摘要】：目的:研究低钠血症治疗量的钠在细胞外液和骨中的分布特征。方法:搜集2011年12月至2016年12月就诊于山西医科大学第二医院的低钠血症患者,制定纳入标准和排除标准,拟入选30-50例。公式计算细胞外液新增的钠和转移到骨中新增的钠,对新增细胞外液钠和骨钠数据进行正态分布检验,以及均数和中位数计算,并对细胞外液的钠和转移到骨中的钠两组数据做t检验、直线回归和相关分析。结果:最终入组病例30例。细胞外液新增的钠离子(X)正态分析偏度为-0.612和峰度为-0.222,Shapiro-Wilk检验p0.05,不服从正态分布。骨中新增钠离子(Y)正态分析偏度为-0.146,峰度为-1.479,Shapiro-Wilk检验p0.05,不服从正态分布。X-Y差值的正态分析偏度为0.846,峰度为0.459,Shapiro-Wilk检验统计量为0.944,p=0.117(p0.05),服从正态分布。依据直线回归分析结果可以写出Y=43.5+0.17X;对自变量(X)与应变量(Y)数据进行回归系数t检验分析,其结果示p值0.05,无显著统计学意义。结论:1.细胞外液新增的钠离子和骨中新增钠离子的数据是否正态分布尚不能证实,其中位数分别为105.43和64.79,四分之一间距分别为72.24和27.28。2.细胞外液新增的钠离子毫摩尔数显著高于骨中新增钠离子。3.应变量(Y)=43.5+0.17自变量(X)直线回归关系尚不能成立。
[Abstract]:Objective: to study the distribution of sodium in extracellular fluid and bone of hyponatremia. Methods: patients with hyponatremia who were admitted to the second Hospital of Shanxi Medical University from December 2011 to December 2016 were collected and included in the study. The formula calculates the additional sodium in extracellular fluid and the new sodium transferred to bone. The data of new extracellular fluid sodium and bone sodium are tested for normal distribution, and the mean and median are calculated. T test, linear regression and correlation analysis were performed for sodium in extracellular fluid and sodium transferred to bone. Results: there were 30 cases in the final group. The normal analytical bias and kurtosis of the new sodium ion X in extracellular fluid were -0.612 and -0.222% Shapiro-Wilk test, respectively. The normal analysis bias of the newly added sodium ion Y) in bone was -0.146, the kurtosis was -1.479% Shapiro-Wilk test (p 0.05), the normal analysis bias of the normal distribution. X-Y difference value was 0.846, the kurtosis was 0.459m Shapiro-Wilk test statistics was 0.944%, and the normal distribution was obtained. According to the results of linear regression analysis, we can write out the data of Yeng 43.5 0.17X.The regression coefficient t test analysis of the data of independent variable X) and strain variable Y) shows that the value of p is 0.05, which has no significant statistical significance. Conclusion 1. The normal distribution of the new sodium ions in extracellular fluid and bone was not confirmed. The median values were 105.43 and 64.79, and the spacing of 1/4 were 72.24 and 27.28.2respectively. The number of new sodium ions in extracellular fluid was significantly higher than that in bone. The linear regression relationship between the dependent variable and the independent variable is 43.5. 0. 17 and cannot be established.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R591.1

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