广州市老年体检人群维生素D水平与代谢综合征的相关性

发布时间：2018-05-16 19:11

  本文选题：-羟维生素D + 代谢综合征　； 参考：《中国老年学杂志》2016年08期

【摘要】：目的探讨老年体检人群维生素D(VD)水平与代谢综合征的关系。方法选择2011~2014年在该院体检中心进行健康体检的老年患者328例,年龄60~84岁,平均(66.1±5.5)岁。测定血清25-羟维生素D3〔25(OH)D3〕水平,收集身高、体重、年龄等资料,计算体重指数(BMI),检测空腹血糖(FPG)、血压、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)等代谢综合征相关指标,进行相关性分析。按照血清25(OH)D3水平分为VD充足组(≥75 nmol/L);VD不足组(50~75 nmol/L);VD缺乏组(50 nmol/L)。结果三组BMI、FPG、TG、平均年龄比较差异有统计学意义(F=6.565、3.081、4.069、7.336,P0.05)。进一步直线相关分析结果显示,VD水平与FPG、TG、BMI、平均年龄呈负相关(r=-0.153、-0.115、-0.122、-0.279,P0.05),与HDL-C、收缩压、舒张压无相关性(r=-0.059、0.024、-0.006,均P0.05)。多元线性回归分析显示,FPG、TG为VD不足的独立危险因素。结论老年人VD营养状况与BMI、FPG及TG等代谢相关指标呈负相关。随着年龄的增加,老年人群VD不足或缺乏的状况逐渐加重。
[Abstract]:Objective to investigate the relationship between vitamin D and VD levels and metabolic syndrome. Methods 328 elderly patients, aged 60 to 84 years, with an average age of 66.1 卤5.5 years, were selected from 2011 to 2014. The serum levels of 25-hydroxyvitamin D _ (3), height, weight and age were collected, body mass index (BMI) was calculated, fasting blood glucose (FBG), blood pressure (BP), triglyceride (TGN), high density lipoprotein cholesterol (HDL-C) were measured. Correlation analysis was carried out. According to the level of serum 25(OH)D3, the patients were divided into two groups: VD deficient group (鈮，

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