成年艾滋病抗病毒治疗患者生存状况及其影响因素

发布时间：2018-05-17 11:17

  本文选题：艾滋病 + 抗病毒治疗　； 参考：《中国公共卫生》2017年01期

【摘要】：目的了解成年艾滋病抗病毒治疗患者生存状况及其影响因素,为改善艾滋病患者生存状况提供参考依据。方法收集2006年9月—2010年9月在宁夏医科大学总医院接受抗病毒治疗的152例≥18周岁成年艾滋病患者病历资料,分析其在观察期间的生存状况,并采用多因素Cox比例风险回归模型分析影响患者生存状况的影响因素。结果 2015年9月30日随访截止时,152例成年艾滋病抗病毒治疗患者中仍在治疗102例(67.11%),失访7例(4.61%),转诊10例(6.58%),停药5例(3.29%),死亡28例(18.42%);28例死亡患者中,死于艾滋病者21例(75.00%),因其他因素致死者7例(25.00%);21例死于艾滋病患者中,抗病毒治疗1年死亡11例(52.38%),2~3年死亡7例(33.33%),4~5年死亡3例(14.29%)。多因素Cox比例风险回归分析结果显示,年龄≥30岁、WHO临床分期Ⅲ期以上、感染途径为异性和同性性途径感染是影响成年艾滋病抗病毒治疗患者生存状况的危险因素;CD4~+细胞计数200个/μL和抗病毒治疗方案为≥2种抗菌药物联合治疗是影响成年艾滋病抗病毒治疗患者生存状况的保护因素。结论年龄、CD4~+细胞计数、WHO临床分期、抗病毒治疗方案和感染途径是成年艾滋病抗病毒治疗患者生存状况的主要影响因素。
[Abstract]:Objective to investigate the survival status and its influencing factors of adult AIDS patients treated with antiviral therapy, and to provide a reference for improving the survival status of AIDS patients. Methods from September 2006 to September 2010, 152 AIDS patients aged 18 years or older who received antiviral therapy in the General Hospital of Ningxia Medical University were collected, and their survival status during the observation period was analyzed. Multivariate Cox proportional risk regression model was used to analyze the influencing factors of patients' survival. Results at the end of follow-up on September 30, 2015, 102 out of 152 adult HIV / AIDS patients were still receiving treatment, 7 were missing, 10 were referred to 6.58, 5 were stopped taking medicine, 28 died from 18.42 and 28 died. Among the 21 cases who died of AIDS, 7 cases died of AIDS from 25.00% to 21 cases, 11 cases died of antiviral therapy in one year, 7 cases died in 2 ~ 3 years, 7 cases died from 33.33% in 4 ~ 5 years, 3 cases died 14.29%. Multivariate Cox proportional risk regression analysis showed that the age 鈮，

本文编号：1901158