不同性别高校新生超重肥胖及高血压与血清丙氨酸氨基转移酶异常的相关性分析

发布时间：2018-05-21 12:43

本文选题：超重 + 肥胖　；参考：《现代预防医学》2017年08期

【摘要】：目的探讨不同性别大学新生超重肥胖及高血压与血清丙氨酸氨基转移酶(ALT)异常的相关性。方法对4 236名入学新生测量身高、体重及血压并检测ALT水平,观察ALT异常状况,分析不同性别大学新生超重肥胖及高血压对ALT异常的影响。结果大学新生ALT异常率为7.41%,男生ALT异常率(12.62%)明显高于女生(2.84%)(P0.001)。随着体重指数(BMI)和血压水平的增高,男女新生ALT异常发生率均呈上升趋势。校正混杂因素后,男生超重、肥胖者ALT异常患病风险是体重正常者的2.798倍(95%CI:2.086~4.156)和7.345倍(95%CI:4.965~11.422),女生超重肥胖者ALT异常患病风险分别是体重正常者的3.712倍(95%CI:2.023~7.145)和13.876倍(95%CI:6.992~28.567),低体重则是ALT异常发生的保护因子。男女生高血压组ALT异常患病率分别是血压正常组的4.765倍和4.023倍。结论大学新生超重肥胖及高血压与血清ALT异常升高呈明显正相关,女生超重肥胖者发生ALT异常的风险较男生高,对BMI及血压的监测有助于ALT异常疾病的防控。
[Abstract]:Objective to investigate the relationship between serum alanine aminotransferase (alt) abnormality and overweight, obesity and hypertension in freshmen of different genders. Methods the height, weight and blood pressure of 4 236 freshmen were measured and ALT levels were measured. The abnormal ALT was observed and the influence of overweight, obesity and hypertension on ALT abnormality was analyzed. Results the abnormal rate of ALT in freshmen was 7.41, and the abnormal rate of ALT in male students was 12.62%, which was significantly higher than that in female students (2.84%, P 0.001). With the increase of body mass index (BMI) and blood pressure, the incidence of abnormal ALT in male and female freshmen showed an increasing trend. After adjusting for confounding factors, boys were overweight, The risk of abnormal ALT in obese persons was 2.798 times as high as that in normal subjects (95 CI: 2.086 / 4.156) and 7.345 times in 95 CI: 4.965 (11.422). The risk of abnormal ALT in overweight and obese girls was 3.712 times of that in normal subjects, and 13.876 times that of 95 CI: 2.0232.7.145) and 13.876 times of 95CIw 6.9922.5677.567. low body weight was the protective factor for the occurrence of ALT abnormalities. The prevalence of abnormal ALT in male and female hypertension group was 4.765 and 4.023 times higher than that in normal blood pressure group respectively. Conclusion there is a significant positive correlation between overweight obesity and hypertension in college freshmen and abnormal increase of serum ALT. The risk of abnormal ALT in overweight and obese female students is higher than that in male students. Monitoring BMI and blood pressure is helpful to the prevention and control of ALT abnormal diseases.
【作者单位】：江汉大学医院;
【分类号】：R589.2;R544.1

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