干燥综合征的肺部病变

发布时间：2018-05-30 01:06

本文选题：干燥综合征 + 气道病变　；参考：《中国实用内科杂志》2017年06期

【摘要】：干燥综合征(Sj?gren’s syndrome,SS)腺体外系统受累较常见,包括肺部病变。SS肺损害定义为出现呼吸道症状、肺功能异常或影像学异常等。患者表现各异,支气管炎和支气管扩张是常见的气道病变。SS合并间质性肺疾病是常见的肺部病变。另外,SS患者有患肺淋巴瘤的高风险,也可出现肺动脉高压、肺囊性病变、肺淀粉样变及胸膜受累等。基线评估SS患者肺部病变是必要的。目前关于SS合并肺损害的治疗尚缺乏大型、随机对照临床研究数据。进展性肺损害患者,糖皮质激素和(或)免疫抑制剂治疗是必要的。SS-肺动脉高压的治疗目前推荐靶向药物治疗为主。
[Abstract]:The extraglandular system involvement of Sjgren's syndrome SSs in Sjogren's syndrome is more common, including pulmonary lesions. SS lung damage is defined as respiratory symptoms, abnormal pulmonary function or imaging abnormalities. Bronchitis and bronchiectasis are common airway lesions. In addition, SS patients have a high risk of lung lymphoma, pulmonary hypertension, pulmonary cystic lesions, pulmonary amyloidosis and pleural involvement. Baseline assessment of pulmonary lesions in SS patients is necessary. At present, the treatment of SS with lung injury is still lack of large-scale, randomized controlled clinical study data. In patients with progressive lung damage, glucocorticoid and / or immunosuppressive therapy is necessary for the treatment of pulmonary hypertension.
【作者单位】：北京协和医院风湿免疫科;首都医科大学宣武医院风湿免疫科;
【分类号】：R563;R593.2

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